Since the breast is one of the most radiosensitive organs, mammography is arguably the area where lowering radiation dose is of the uttermost importance. Phase-based x-ray imaging methods can provide opportunities in this sense, since they do not require x-rays to be stopped in tissue for image contrast to be generated. Therefore, x-ray energy can be considerably increased compared to those usually exploited by conventional mammography. In this article we show how a novel, optimized approach can lead to considerable dose reductions. This was achieved by matching the edge-illumination phase method, which reaches very high angular sensitivity also at high x-ray energies, to an appropriate image processing algorithm and to a virtually noise-free detection technology capable of reaching almost 100% efficiency at the same energies. Importantly, while proof-of-concept was obtained at a synchrotron, the method has potential for a translation to conventional sources.

Diemoz Paul, C., Bravin, A., Sztrokay-Gaul, A., Ruat, M., Grandl, S., Mayr, D., et al. (2016). A method for high-energy, low-dose mammography using edge illumination x-ray phase-contrast imaging. PHYSICS IN MEDICINE AND BIOLOGY, 61(24), 8750-8761 [10.1088/1361-6560/61/24/8750].

A method for high-energy, low-dose mammography using edge illumination x-ray phase-contrast imaging

Bravin A
Secondo
Membro del Collaboration Group
;
2016

Abstract

Since the breast is one of the most radiosensitive organs, mammography is arguably the area where lowering radiation dose is of the uttermost importance. Phase-based x-ray imaging methods can provide opportunities in this sense, since they do not require x-rays to be stopped in tissue for image contrast to be generated. Therefore, x-ray energy can be considerably increased compared to those usually exploited by conventional mammography. In this article we show how a novel, optimized approach can lead to considerable dose reductions. This was achieved by matching the edge-illumination phase method, which reaches very high angular sensitivity also at high x-ray energies, to an appropriate image processing algorithm and to a virtually noise-free detection technology capable of reaching almost 100% efficiency at the same energies. Importantly, while proof-of-concept was obtained at a synchrotron, the method has potential for a translation to conventional sources.
Articolo in rivista - Articolo scientifico
dose reduction; mammography; phase retrieval; x-ray phase-contrast imaging;
English
2016
61
24
8750
8761
open
Diemoz Paul, C., Bravin, A., Sztrokay-Gaul, A., Ruat, M., Grandl, S., Mayr, D., et al. (2016). A method for high-energy, low-dose mammography using edge illumination x-ray phase-contrast imaging. PHYSICS IN MEDICINE AND BIOLOGY, 61(24), 8750-8761 [10.1088/1361-6560/61/24/8750].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/343186
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