Subtilisin-catalyzed esterification of several enatiomeric benzyl and naphthyl glycopyranosides has been investigated. The D-sugar derivatives were all good substrates and subtilisin regioselectivity was similar with all the compounds tested, the 3-OH being acylated predominantly. On the other hand, most of the L-glycopyranosides were transformed during longer reaction times with a lower regioselectivity, the 2-OH being preferentially but not exclusively acylated

Danieli, B., Peri, F., Roda, G., Carrea, G., & Riva, S. (1999). On the regioselectivity of the protease Subtilisin towards the acylation of enantiomeric pairs of benzyl and naphtyl glycopyranosides. Part 2. TETRAHEDRON, 55(7), 2045-2060 [10.1016/S0040-4020(98)01217-4].

On the regioselectivity of the protease Subtilisin towards the acylation of enantiomeric pairs of benzyl and naphtyl glycopyranosides. Part 2

Peri, F;
1999

Abstract

Subtilisin-catalyzed esterification of several enatiomeric benzyl and naphthyl glycopyranosides has been investigated. The D-sugar derivatives were all good substrates and subtilisin regioselectivity was similar with all the compounds tested, the 3-OH being acylated predominantly. On the other hand, most of the L-glycopyranosides were transformed during longer reaction times with a lower regioselectivity, the 2-OH being preferentially but not exclusively acylated
Articolo in rivista - Articolo scientifico
Scientifica
enzymatic reaction; stereoselective reactions; synthetic chemistry
English
Danieli, B., Peri, F., Roda, G., Carrea, G., & Riva, S. (1999). On the regioselectivity of the protease Subtilisin towards the acylation of enantiomeric pairs of benzyl and naphtyl glycopyranosides. Part 2. TETRAHEDRON, 55(7), 2045-2060 [10.1016/S0040-4020(98)01217-4].
Danieli, B; Peri, F; Roda, G; Carrea, G; Riva, S
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10281/34261
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