Short‐duration cooling of the nerve to the extensor digitorum longus muscle of the rat in vivo induced partially reversible denervation of the muscle and atrophy in the type 2 muscle fibers. Increases in cyclic adenosine monophosphate, cyclic guanosine monophosphate phosphodiesterase, adenylate cyclase, and guanlate cyclase were observed in the denervated muscle. Treatment with gangliosides of the bovine brain cortex seemed to improve the excitability of the surviving motor units and to encourage recovery of neuromuscular trophic control, but it did not affect the nerve conduction velocity or the contractile properties of the denervated muscle. Copyright © 1979 Houghton Mifflin Professional Publishers

Caccia, M., Meola, G., Cerri, C., Frattola, L., Scarlato, G., & Aporti, F. (1979). TREATMENT OF DENERVATED MUSCLE BY GANGLIOSIDES. MUSCLE & NERVE, 2(5), 382-389 [10.1002/mus.880020510].

TREATMENT OF DENERVATED MUSCLE BY GANGLIOSIDES

CERRI, CESARE GIUSEPPE;
1979

Abstract

Short‐duration cooling of the nerve to the extensor digitorum longus muscle of the rat in vivo induced partially reversible denervation of the muscle and atrophy in the type 2 muscle fibers. Increases in cyclic adenosine monophosphate, cyclic guanosine monophosphate phosphodiesterase, adenylate cyclase, and guanlate cyclase were observed in the denervated muscle. Treatment with gangliosides of the bovine brain cortex seemed to improve the excitability of the surviving motor units and to encourage recovery of neuromuscular trophic control, but it did not affect the nerve conduction velocity or the contractile properties of the denervated muscle. Copyright © 1979 Houghton Mifflin Professional Publishers
Articolo in rivista - Articolo scientifico
Scientifica
gangliosides
English
Caccia, M., Meola, G., Cerri, C., Frattola, L., Scarlato, G., & Aporti, F. (1979). TREATMENT OF DENERVATED MUSCLE BY GANGLIOSIDES. MUSCLE & NERVE, 2(5), 382-389 [10.1002/mus.880020510].
Caccia, M; Meola, G; Cerri, C; Frattola, L; Scarlato, G; Aporti, F
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10281/33803
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