We aimed to characterize the epidemiology, diagnostic peculiarities and outcome determinants of bacterial myocarditis. Two cases from our institution and literature reports were collected ending up with a total of 66 cases. In 37 (56%) patients, the diagnosis was confirmed by magnetic resonance and histopathological criteria. The other patients were classified as having possible myocarditis. Only occurrence of rhythm disturbances was associated with the specific diagnosis of myocarditis (p = 0.04). Thirty-two (48%) patients presented with severe sepsis that was associated with a worse prognosis. At multivariate analysis, left ventricular ejection fraction (LVEF) at admission and heart rhythm disturbances were associated with incomplete recovery (odds ratio (OR) 1.1, 95% (CI) 1.03–1.2, p = 0.004 and OR 6.6, 95% CI 1.35–32.5, p = 0.02, respectively). In summary, bacterial myocarditis is uncommon. Most commonly, it is secondary to septic dissemination of bacteria or to transient secondary myocardial toxicity.

Ferrero, P., Piazza, I., Lorini, F., Senni, M. (2020). Epidemiologic and clinical profiles of bacterial myocarditis. Report of two cases and data from a pooled analysis. INDIAN HEART JOURNAL, 72(2), 82-92 [10.1016/j.ihj.2020.04.005].

Epidemiologic and clinical profiles of bacterial myocarditis. Report of two cases and data from a pooled analysis

Lorini F;Senni M
2020

Abstract

We aimed to characterize the epidemiology, diagnostic peculiarities and outcome determinants of bacterial myocarditis. Two cases from our institution and literature reports were collected ending up with a total of 66 cases. In 37 (56%) patients, the diagnosis was confirmed by magnetic resonance and histopathological criteria. The other patients were classified as having possible myocarditis. Only occurrence of rhythm disturbances was associated with the specific diagnosis of myocarditis (p = 0.04). Thirty-two (48%) patients presented with severe sepsis that was associated with a worse prognosis. At multivariate analysis, left ventricular ejection fraction (LVEF) at admission and heart rhythm disturbances were associated with incomplete recovery (odds ratio (OR) 1.1, 95% (CI) 1.03–1.2, p = 0.004 and OR 6.6, 95% CI 1.35–32.5, p = 0.02, respectively). In summary, bacterial myocarditis is uncommon. Most commonly, it is secondary to septic dissemination of bacteria or to transient secondary myocardial toxicity.
Articolo in rivista - Review Essay
Bacterial; Diagnosis; Epidemiology; Myocarditis; Sepsis;
English
82
92
11
Ferrero, P., Piazza, I., Lorini, F., Senni, M. (2020). Epidemiologic and clinical profiles of bacterial myocarditis. Report of two cases and data from a pooled analysis. INDIAN HEART JOURNAL, 72(2), 82-92 [10.1016/j.ihj.2020.04.005].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/337363
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