Although discrimination of the model for end stage liver disease (MELD) is generally considered acceptable, its calibration is still unclear. In a validation study, we assessed the discrimination and calibration performance of 3 versions of the model: original MELD-TIPS, used to predict survival after transjugular intra-hepatic portosystemic shunt (TIPS); classic MELD-Mayo; MELD-UNOS, used by United Network for Organ Sharing (UNOS). Recalibration and model updating were also explored.
D'Amico, G., Maruzzelli, L., Airoldi, A., Petridis, I., Tosetti, G., Rampoldi, A., et al. (2021). Performance of the model for end-stage liver disease score for mortality prediction and the potential role of etiology. JOURNAL OF HEPATOLOGY, 75(6), 1355-1366 [10.1016/j.jhep.2021.07.018].
Performance of the model for end-stage liver disease score for mortality prediction and the potential role of etiology
Miraglia, Roberto;Pozzoni, Pietro;Belli, Luca Saverio
2021
Abstract
Although discrimination of the model for end stage liver disease (MELD) is generally considered acceptable, its calibration is still unclear. In a validation study, we assessed the discrimination and calibration performance of 3 versions of the model: original MELD-TIPS, used to predict survival after transjugular intra-hepatic portosystemic shunt (TIPS); classic MELD-Mayo; MELD-UNOS, used by United Network for Organ Sharing (UNOS). Recalibration and model updating were also explored.
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