Thyroid cancer is the most common endocrine malignant disease, but preoperative diagnosis remains a challenge. Fine-needle aspiration cytology has greatly improved the clinical management of thyroid nodules, but the preoperative characterisation of follicular lesions is very difficult. Many patients are thus referred to surgery more for diagnosis than for therapeutic necessity. We undertook an international multicentre study to assess the usefulness of immunohistocytochemical staining for two potential markers of malignant thyrocytes.

Bartolazzi, A., Gasbarri, A., Papotti, M., Bussolati, G., Lucante, T., Khan, A., et al. (2001). Application of an immunodiagnostic method for improving preoperative diagnosis of nodular thyroid lesions. THE LANCET, 357(9269), 1644-1650.

Application of an immunodiagnostic method for improving preoperative diagnosis of nodular thyroid lesions

BELLOCCO, RINO;
2001

Abstract

Thyroid cancer is the most common endocrine malignant disease, but preoperative diagnosis remains a challenge. Fine-needle aspiration cytology has greatly improved the clinical management of thyroid nodules, but the preoperative characterisation of follicular lesions is very difficult. Many patients are thus referred to surgery more for diagnosis than for therapeutic necessity. We undertook an international multicentre study to assess the usefulness of immunohistocytochemical staining for two potential markers of malignant thyrocytes.
Articolo in rivista - Articolo scientifico
Antigens, Differentiation; Neoplasm Invasiveness; Diagnosis, Differential; Thyroid Nodule; Thyroid Neoplasms; Humans; Prognosis; Galectin 3; Predictive Value of Tests; Biopsy, Needle; Thyroid Gland; Antigens, CD44; Prospective Studies; Glycoproteins; Immunoenzyme Techniques
English
1644
1650
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Bartolazzi, A., Gasbarri, A., Papotti, M., Bussolati, G., Lucante, T., Khan, A., et al. (2001). Application of an immunodiagnostic method for improving preoperative diagnosis of nodular thyroid lesions. THE LANCET, 357(9269), 1644-1650.
Bartolazzi, A; Gasbarri, A; Papotti, M; Bussolati, G; Lucante, T; Khan, A; Inohara, H; Marandino, F; Orlandi, F; Nardi, F; Vecchione, A; Tecce, R; Larsson, O; Bellocco, R; In the Italian Thyroide, C
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/31687
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