Substrate engineering for steering cell growth is a wide and well-established area of research in the field of modern biotechnology. Here we introduce a micromachining technique to pattern an inert and transparent polymer matrix blended with a photoactive polymer. We demonstrate that the obtained scaffold combines the capability to align with that to photostimulate living cells. This technology can open up new and promising applications, especially where cell alignment is required to trigger specific biological functions, e.g., generate powerful and efficient muscle contractions following an external stimulus.

Vurro, V., Scaccabarozzi, A., Lodola, F., Storti, F., Marangi, F., Ross, A., et al. (2021). A Polymer Blend Substrate for Skeletal Muscle Cells Alignment and Photostimulation. ADVANCED PHOTONICS RESEARCH, 2(2 (February 2021)) [10.1002/adpr.202000103].

A Polymer Blend Substrate for Skeletal Muscle Cells Alignment and Photostimulation

Lodola, F;
2021

Abstract

Substrate engineering for steering cell growth is a wide and well-established area of research in the field of modern biotechnology. Here we introduce a micromachining technique to pattern an inert and transparent polymer matrix blended with a photoactive polymer. We demonstrate that the obtained scaffold combines the capability to align with that to photostimulate living cells. This technology can open up new and promising applications, especially where cell alignment is required to trigger specific biological functions, e.g., generate powerful and efficient muscle contractions following an external stimulus.
Articolo in rivista - Articolo scientifico
cell alignment, geneless optostimulation, organic semiconductors, photostimulation, photothermal effect
English
Vurro, V., Scaccabarozzi, A., Lodola, F., Storti, F., Marangi, F., Ross, A., et al. (2021). A Polymer Blend Substrate for Skeletal Muscle Cells Alignment and Photostimulation. ADVANCED PHOTONICS RESEARCH, 2(2 (February 2021)) [10.1002/adpr.202000103].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/315601
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