Functional tricuspid regurgitation (FTR) is characterized by structurally normal leaflets and is due to the deformation of the valvulo-ventricular complex. While mild FTR is frequent and usually benign, patients with severe FTR may develop progressive ventricular dysfunction and incur increased mortality. Therefore, FTR should not be ignored, should be appropriately diagnosed and quantified by Doppler echocardiography, and should be evaluated for corrective surgical procedures. At present, referral for surgical correction of FTR is often delayed until patients develop intractable heart failure. However, this strategy frequently translates in poor clinical outcome characterized by notable operative mortality and reduced long-term survival. Appropriate patient selection and proper timing for tricuspid valve (TV) repair or replacement are crucial for optimal outcome, but objective criteria for clinical decison-making remain poorly defined. In the present paper, we review the anatomy of the normal TV, the pathophysiology of FTR, the assessment of its severity and functional significance, and propose an algorithm for selecting patients for surgical treatment.

Badano, L., Muraru, D., Enriquez Sarano, M. (2013). Assessment of functional tricuspid regurgitation. EUROPEAN HEART JOURNAL, 34(25), 1875-1884 [10.1093/eurheartj/ehs474].

Assessment of functional tricuspid regurgitation

BADANO, LUIGI
Primo
;
MURARU, DENISA
Secondo
;
2013

Abstract

Functional tricuspid regurgitation (FTR) is characterized by structurally normal leaflets and is due to the deformation of the valvulo-ventricular complex. While mild FTR is frequent and usually benign, patients with severe FTR may develop progressive ventricular dysfunction and incur increased mortality. Therefore, FTR should not be ignored, should be appropriately diagnosed and quantified by Doppler echocardiography, and should be evaluated for corrective surgical procedures. At present, referral for surgical correction of FTR is often delayed until patients develop intractable heart failure. However, this strategy frequently translates in poor clinical outcome characterized by notable operative mortality and reduced long-term survival. Appropriate patient selection and proper timing for tricuspid valve (TV) repair or replacement are crucial for optimal outcome, but objective criteria for clinical decison-making remain poorly defined. In the present paper, we review the anatomy of the normal TV, the pathophysiology of FTR, the assessment of its severity and functional significance, and propose an algorithm for selecting patients for surgical treatment.
Articolo in rivista - Articolo scientifico
Echocardiography; Functional tricuspid regurgitation; Pathophysiology; Right ventricle; Three dimensional; Tricuspid valve; Cardiac Imaging Techniques; Humans; Patient Selection; Time-to-Treatment; Tricuspid Valve; Tricuspid Valve Insufficiency; Cardiology and Cardiovascular Medicine; Medicine (all)
English
9-gen-2013
2013
34
25
1875
1884
none
Badano, L., Muraru, D., Enriquez Sarano, M. (2013). Assessment of functional tricuspid regurgitation. EUROPEAN HEART JOURNAL, 34(25), 1875-1884 [10.1093/eurheartj/ehs474].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/294563
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