Genetic sequences are known to possess non-trivial composition together with symmetries in the frequencies of their components. Recently, it has been shown that symmetry and structure are hierarchically intertwined in DNA, suggesting a common origin for both features. However, the mechanism leading to this relationship is unknown. Here we investigate a biologically motivated dynamics for the evolution of genetic sequences. We show that a metastable (long-lived) regime emerges in which sequences have symmetry and structure interlaced in a way that matches that of extant genomes.

Cristadoro, G., Degli Esposti, M., Altmann, E. (2020). Dynamics of transposable elements generates structure and symmetries in genetic sequences. PHYSICAL REVIEW RESEARCH, 2(3), 033477-1-033477-6 [10.1103/PhysRevResearch.2.033477].

Dynamics of transposable elements generates structure and symmetries in genetic sequences

Cristadoro, Giampaolo
;
2020

Abstract

Genetic sequences are known to possess non-trivial composition together with symmetries in the frequencies of their components. Recently, it has been shown that symmetry and structure are hierarchically intertwined in DNA, suggesting a common origin for both features. However, the mechanism leading to this relationship is unknown. Here we investigate a biologically motivated dynamics for the evolution of genetic sequences. We show that a metastable (long-lived) regime emerges in which sequences have symmetry and structure interlaced in a way that matches that of extant genomes.
Articolo in rivista - Articolo scientifico
Chargaff Parity Rules, Long-range correlations, DNA, transposable elements, Mathematical biology
English
23-set-2020
2020
2
3
033477-1
033477-6
none
Cristadoro, G., Degli Esposti, M., Altmann, E. (2020). Dynamics of transposable elements generates structure and symmetries in genetic sequences. PHYSICAL REVIEW RESEARCH, 2(3), 033477-1-033477-6 [10.1103/PhysRevResearch.2.033477].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/288867
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