A large number of evidences have clearly shown that overweight and obesity are associated with an increased risk of cardiovascular diseases. It is well-known that the progressive weight increase is associated with neurohumoral and metabolic alterations and that interventions based on weight control or surgical approaches are able to reverse, almost in part, these adverse alterations. Several mechanisms contribute to this effect and to the increased cardiovascular risk observed in the obese subjects. Recent findings, employing new methodological approaches, evaluated the effects of obesity on microcirculation. These studies have clarified some of the mechanisms involved in the alterations observed both in the structure and function of this important vascular bed.
Seravalle, G., Grassi, G. (2020). Microvascular Alterations in Obesity. In Updates in Hypertension and Cardiovascular Protection (pp. 137-147). Springer [10.1007/978-3-030-47801-8_11].
Microvascular Alterations in Obesity
Seravalle, GinoPrimo
;Grassi, Guido
Ultimo
2020
Abstract
A large number of evidences have clearly shown that overweight and obesity are associated with an increased risk of cardiovascular diseases. It is well-known that the progressive weight increase is associated with neurohumoral and metabolic alterations and that interventions based on weight control or surgical approaches are able to reverse, almost in part, these adverse alterations. Several mechanisms contribute to this effect and to the increased cardiovascular risk observed in the obese subjects. Recent findings, employing new methodological approaches, evaluated the effects of obesity on microcirculation. These studies have clarified some of the mechanisms involved in the alterations observed both in the structure and function of this important vascular bed.
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