Acute Respiratory Distress Syndrome (ARDS) is a complex and debilitating disease of the lungs, which continues to have a high mortality rate and huge disease burden on patients. Incidence is rising, possibly due to greater awareness leading to more diagnoses rather than a change in the underlying rate. It arises from multiple etiologies, though pathogenic infection, termed pneumonia, is the most prevalent and widely studied. The distinct pathophysiology and rapid evolution of ARDS makes it uniquely challenging with regard to therapeutics development and, to date, no medicines are licensed for specific therapy. Antibiotics, ventilation, and other organ support remain intervention standards.

Rezoagli, E., Murphy, E., Laffey, J., O'Toole, D. (2019). The safety and efficiency of addressing ards using stem cell therapies in clinical trials. In Burgess JK, Heijink I (a cura di), Stem Cell-Based Therapy for Lung Disease (pp. 219-238). Springer International Publishing [10.1007/978-3-030-29403-8_12].

The safety and efficiency of addressing ards using stem cell therapies in clinical trials

Rezoagli E.
Primo
;
2019

Abstract

Acute Respiratory Distress Syndrome (ARDS) is a complex and debilitating disease of the lungs, which continues to have a high mortality rate and huge disease burden on patients. Incidence is rising, possibly due to greater awareness leading to more diagnoses rather than a change in the underlying rate. It arises from multiple etiologies, though pathogenic infection, termed pneumonia, is the most prevalent and widely studied. The distinct pathophysiology and rapid evolution of ARDS makes it uniquely challenging with regard to therapeutics development and, to date, no medicines are licensed for specific therapy. Antibiotics, ventilation, and other organ support remain intervention standards.
Capitolo o saggio
ARDS; stem cells; clinical trials; safety; efficiency
English
Stem Cell-Based Therapy for Lung Disease
Burgess JK; Heijink I
2019
978-3-030-29402-1
Springer International Publishing
219
238
Rezoagli, E., Murphy, E., Laffey, J., O'Toole, D. (2019). The safety and efficiency of addressing ards using stem cell therapies in clinical trials. In Burgess JK, Heijink I (a cura di), Stem Cell-Based Therapy for Lung Disease (pp. 219-238). Springer International Publishing [10.1007/978-3-030-29403-8_12].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/287249
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