Gastric cancer is a common neoplastic disease and, more precisely, is the third leading cause of cancer death in the world, with differences amongst geographic areas. The definition of advanced gastric cancer is still debated. Different stadiating systems lead to slightly different stadiation of the disease, thus leading to variations between the single countries in the treatment and outcomes. In the present review all the possibilities of treatment for advanced gastric cancer have been analyzed. Surgery, the cornerstone of treatment for advanced gastric cancer, is analyzed first, followed by an investigation of the different forms and drugs of chemotherapy and radiotherapy. New frontiers in treatment suggest the growing consideration for intraperitoneal administration of chemotherapeutics and combination of traditional drugs with new ones. Moreover, the necessity to prevent the relapse of the disease leads to the consideration of administering intraperitoneal chemotherapy earlier in the therapeutical algorithm.

Coccolini, F., Montori, G., Ceresoli, M., Cima, S., Valli, M., Nita, G., et al. (2016). Advanced gastric cancer: What we know and what we still have to learn. WORLD JOURNAL OF GASTROENTEROLOGY, 22(3), 1139-1159 [10.3748/wjg.v22.i3.1139].

Advanced gastric cancer: What we know and what we still have to learn

Ceresoli M.;Ansaloni L.
2016

Abstract

Gastric cancer is a common neoplastic disease and, more precisely, is the third leading cause of cancer death in the world, with differences amongst geographic areas. The definition of advanced gastric cancer is still debated. Different stadiating systems lead to slightly different stadiation of the disease, thus leading to variations between the single countries in the treatment and outcomes. In the present review all the possibilities of treatment for advanced gastric cancer have been analyzed. Surgery, the cornerstone of treatment for advanced gastric cancer, is analyzed first, followed by an investigation of the different forms and drugs of chemotherapy and radiotherapy. New frontiers in treatment suggest the growing consideration for intraperitoneal administration of chemotherapeutics and combination of traditional drugs with new ones. Moreover, the necessity to prevent the relapse of the disease leads to the consideration of administering intraperitoneal chemotherapy earlier in the therapeutical algorithm.
Articolo in rivista - Review Essay
Advanced gastric cancer; Chemotherapy; Definition; Hypertermic intraperitoneal chemotherapy; Intra peritoneal; Surgery
English
1139
1159
21
Coccolini, F., Montori, G., Ceresoli, M., Cima, S., Valli, M., Nita, G., et al. (2016). Advanced gastric cancer: What we know and what we still have to learn. WORLD JOURNAL OF GASTROENTEROLOGY, 22(3), 1139-1159 [10.3748/wjg.v22.i3.1139].
Coccolini, F; Montori, G; Ceresoli, M; Cima, S; Valli, M; Nita, G; Heyer, A; Catena, F; Ansaloni, L
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/284514
Citazioni
  • Scopus 51
  • ???jsp.display-item.citation.isi??? 45
Social impact