Background and objectives Hospital readmissions are a frequent complication of pneumonia. Most data regarding readmissions are obtained from the United States, whereas few data are available from the European healthcare utilization (HCU) systems. In a large cohort of Italian patients with a previous hospitalization for pneumonia, our aim was to evaluate the incidence and predictors of early readmissions due to pneumonia. Methods This is a observational retrospective, population based, cohort study. Data were retrieved from the HCU databases of the Italian Lombardy region. 203,768 patients were hospitalized for pneumonia between 2003 and 2012. The outcome was the first rehospitalization for pneumonia. The patients were followed up after the index hospital admission to estimate the hazard ratio, and relative 95% confidence interval, of the outcome associated with the risk factors that we had identified. Results 7,275 patients (3.6%) had an early pneumonia readmission. Male gender, age >= 70 years, length of stay of the first admission and a higher burden of comorbidities were significantly associated with the outcome. Chronic use of antidepressants, antiarrhythmics, glucocorticoids and drugs for obstructive airway diseases were also more frequently prescribed in patients requiring rehospitalization. Previous use of inhaled broncodilators, including both beta2-agonists and anticholinergics, but not inhaled steroids, were associated with an increased risk of hospital readmission. Conclusions Frail elderly patients with multiple comorbidities and complex drug regimens were at higher risk of early rehospitalization and, thus, may require closer follow-up and prevention strategies.

Faverio, P., MONZIO COMPAGNONI, M., DELLA ZOPPA, M., Pesci, A., Cantarutti, A., Merlino, L., et al. (2020). Rehospitalization for pneumonia after first pneumonia admission: Incidence and predictors in a population-based cohort study. PLOS ONE, 15(6) [10.1371/journal.pone.0235468].

Rehospitalization for pneumonia after first pneumonia admission: Incidence and predictors in a population-based cohort study

Paola Faverio
;
Matteo Monzio Compagnoni;Matteo Della Zoppa;Alberto Pesci;Anna Cantarutti;Fabrizio Luppi;Giovanni Corrao
2020

Abstract

Background and objectives Hospital readmissions are a frequent complication of pneumonia. Most data regarding readmissions are obtained from the United States, whereas few data are available from the European healthcare utilization (HCU) systems. In a large cohort of Italian patients with a previous hospitalization for pneumonia, our aim was to evaluate the incidence and predictors of early readmissions due to pneumonia. Methods This is a observational retrospective, population based, cohort study. Data were retrieved from the HCU databases of the Italian Lombardy region. 203,768 patients were hospitalized for pneumonia between 2003 and 2012. The outcome was the first rehospitalization for pneumonia. The patients were followed up after the index hospital admission to estimate the hazard ratio, and relative 95% confidence interval, of the outcome associated with the risk factors that we had identified. Results 7,275 patients (3.6%) had an early pneumonia readmission. Male gender, age >= 70 years, length of stay of the first admission and a higher burden of comorbidities were significantly associated with the outcome. Chronic use of antidepressants, antiarrhythmics, glucocorticoids and drugs for obstructive airway diseases were also more frequently prescribed in patients requiring rehospitalization. Previous use of inhaled broncodilators, including both beta2-agonists and anticholinergics, but not inhaled steroids, were associated with an increased risk of hospital readmission. Conclusions Frail elderly patients with multiple comorbidities and complex drug regimens were at higher risk of early rehospitalization and, thus, may require closer follow-up and prevention strategies.
Articolo in rivista - Articolo scientifico
pneumonia; rehospitalization; predictors of rehospitalization;
English
Faverio, P., MONZIO COMPAGNONI, M., DELLA ZOPPA, M., Pesci, A., Cantarutti, A., Merlino, L., et al. (2020). Rehospitalization for pneumonia after first pneumonia admission: Incidence and predictors in a population-based cohort study. PLOS ONE, 15(6) [10.1371/journal.pone.0235468].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/277710
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