Objective: To report mode of delivery and immediate neonatal outcome in COVID-19 infected women. Design: This is a retrospective study. Setting: Twelve hospitals in northern Italy. Participants: Pregnant women with COVID-19 confirmed infection who delivered. Exposure: COVID 19 infection in pregnancy. Methods: SARS-CoV-2 infected women who were admitted and delivered during the period 1-20 march 2020 were eligible. Data were collected from the clinical records using a standardized questionnaire on maternal general characteristics, any medical or obstetric co-morbidity, course of pregnancy, clinical signs and symptoms, treatment of COVID 19 infection, mode of delivery, neonatal data and breastfeeding. Main Outcome and Measure: Data on mode of delivery and neonatal outcome. Results: 42 women with COVID-19 delivered at the participating centres: 24(57,1%, 95% CI= 41,0-72,3) delivered vaginally. An elective cesarean section was performed in 18/42 (42,9%, 95%CI 27,7-59,0) cases: in 8 cases the indication was unrelated to COVID-19 infection. Pneumonia was diagnosed in 19/42(45,2%, 95%CI 29,8-61,3) cases: of these 7/19(36,8%,95CI 16,3-61,6) required oxygen support and 4/19(21,1%,95%CI=6,1-45,6) were admitted to a critical care unit. Two women with COVID-19 breastfed without a mask because infection was diagnosed in the post-partum period: their new-borns tested positive for SARS-Cov-2 infection. In one case a new-born had a positive test after a vaginal operative delivery. Conclusions: Although post-partum infection cannot be excluded with 100% certainty, these findings suggest that vaginal delivery is associated with a low risk of intrapartum SARS-Cov-2 transmission to the new-born.
Ferrazzi, E., Frigerio, L., Savasi, V., Vergani, P., Prefumo, F., Barresi, S., et al. (2020). Vaginal delivery in SARS-CoV-2 infected pregnant women in Northern Italy: a retrospective analysis. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 127(9), 1116-1121 [10.1111/1471-0528.16278].
|Citazione:||Ferrazzi, E., Frigerio, L., Savasi, V., Vergani, P., Prefumo, F., Barresi, S., et al. (2020). Vaginal delivery in SARS-CoV-2 infected pregnant women in Northern Italy: a retrospective analysis. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 127(9), 1116-1121 [10.1111/1471-0528.16278].|
|Tipo:||Articolo in rivista - Articolo scientifico|
|Carattere della pubblicazione:||Scientifica|
|Presenza di un coautore afferente ad Istituzioni straniere:||No|
|Titolo:||Vaginal delivery in SARS-CoV-2 infected pregnant women in Northern Italy: a retrospective analysis|
|Autori:||Ferrazzi, E; Frigerio, L; Savasi, V; Vergani, P; Prefumo, F; Barresi, S; Bianchi, S; Ciriello, E; Facchinetti, F; Gervasi, M; Iurlaro, E; Kustermann, A; Mangili, G; Mosca, F; Patane, L; Spazzini, D; Spinillo, A; Trojano, G; Vignali, M; Villa, A; Zuccotti, G; Parazzini, F; Cetin, I|
PARAZZINI, FABIO (Corresponding)
|Data di pubblicazione:||2020|
|Rivista:||BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1111/1471-0528.16278|
|Appare nelle tipologie:||01 - Articolo su rivista|