Head and neck squamous cell carcinoma (HNSCC) is one of the most diffused cancer types, characterized by a high reoccurrence rate, mainly due to the inability of current therapeutic approaches to completely eradicate cancer cells. HNSCC patients often have defective immune functions, thus allowing cancer immune escape and cancer spreading. Particularly important in driving immune escape during HNSCC progression are T-helper and T-regulatory cells. New insights into their mechanisms of action might support the development of effective and long-lasting immunotherapy.

Maggioni, D., Pignataro, L., & Garavello, W. (2017). T-helper and T-regulatory cells modulation in head and neck squamous cell carcinoma. ONCOIMMUNOLOGY, 6(7), e1325066 [10.1080/2162402X.2017.1325066].

T-helper and T-regulatory cells modulation in head and neck squamous cell carcinoma

Garavello W.
2017

Abstract

Head and neck squamous cell carcinoma (HNSCC) is one of the most diffused cancer types, characterized by a high reoccurrence rate, mainly due to the inability of current therapeutic approaches to completely eradicate cancer cells. HNSCC patients often have defective immune functions, thus allowing cancer immune escape and cancer spreading. Particularly important in driving immune escape during HNSCC progression are T-helper and T-regulatory cells. New insights into their mechanisms of action might support the development of effective and long-lasting immunotherapy.
No
Articolo in rivista - Articolo scientifico
Scientifica
HNSCC; immune escape; immunotherapy; Tregs
English
e1325066
Maggioni, D., Pignataro, L., & Garavello, W. (2017). T-helper and T-regulatory cells modulation in head and neck squamous cell carcinoma. ONCOIMMUNOLOGY, 6(7), e1325066 [10.1080/2162402X.2017.1325066].
Maggioni, D; Pignataro, L; Garavello, W
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10281/262592
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