Objective: To evaluate the long-term objective and subjective outcomes to build recurrence-free survival curves after mesh-free uterosacral ligament suspension and to evaluate the long-term impact of prognostic factors on outcome measures. Methods: A retrospective study analyzed 5-year follow-up after repair of primary prolapse through high uterosacral ligament suspension. Bulging symptoms and post-operative prolapse stage II or above were considered subjective and objective recurrences, respectively. The cumulative proportion of relapse-free patients in time was analyzed by Kaplan-Meier curves. Results: A total of 353 women were analyzed. Five-year recurrence rates were 15.0% for objective recurrence, 13.0% for subjective recurrence, and 4.0% for the combined objective and subjective recurrences. Premenopausal status was shown to be a risk factor for anatomic (P=0.022), symptomatic (P=0.001), and combined (P=0.047) recurrence. Conversely, anterior repair was shown to be a protective factor for symptomatic (P=0.012) and combined (P=0.002) recurrence. Most of the recurrences occurred within 2 years after surgery. Conclusion: Long-term outcomes after high uterosacral ligament suspension were satisfactory. Premenopausal status and lack of anterior repair represented risk factors for recurrence in the long term.

Deo, G., Bernasconi, D., Cola, A., Palmieri, S., Spelzini, F., Milani, R., et al. (2019). Long-term outcomes and five-year recurrence-free survival curves after native-tissue prolapse repair. INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS, 147(2), 238-245 [10.1002/ijgo.12938].

Long-term outcomes and five-year recurrence-free survival curves after native-tissue prolapse repair

Bernasconi D. P.;Cola A.;Palmieri S.;Spelzini F.;Manodoro S.
Penultimo
;
Frigerio M.
2019

Abstract

Objective: To evaluate the long-term objective and subjective outcomes to build recurrence-free survival curves after mesh-free uterosacral ligament suspension and to evaluate the long-term impact of prognostic factors on outcome measures. Methods: A retrospective study analyzed 5-year follow-up after repair of primary prolapse through high uterosacral ligament suspension. Bulging symptoms and post-operative prolapse stage II or above were considered subjective and objective recurrences, respectively. The cumulative proportion of relapse-free patients in time was analyzed by Kaplan-Meier curves. Results: A total of 353 women were analyzed. Five-year recurrence rates were 15.0% for objective recurrence, 13.0% for subjective recurrence, and 4.0% for the combined objective and subjective recurrences. Premenopausal status was shown to be a risk factor for anatomic (P=0.022), symptomatic (P=0.001), and combined (P=0.047) recurrence. Conversely, anterior repair was shown to be a protective factor for symptomatic (P=0.012) and combined (P=0.002) recurrence. Most of the recurrences occurred within 2 years after surgery. Conclusion: Long-term outcomes after high uterosacral ligament suspension were satisfactory. Premenopausal status and lack of anterior repair represented risk factors for recurrence in the long term.
Articolo in rivista - Articolo scientifico
Long-term follow-up; Native-tissue repair; Prolapse surgery; Recurrence; Risk factors; Uterosacral ligament suspension;
Long-term follow-up; Native-tissue repair; Prolapse surgery; Recurrence; Risk factors; Uterosacral ligament suspension; Female; Gynecologic Surgical Procedures; Humans; Kaplan-Meier Estimate; Ligaments; Middle Aged; Obesity; Pelvic Organ Prolapse; Premenopause; Recurrence; Retrospective Studies; Risk Factors; Treatment Outcome
English
2019
147
2
238
245
none
Deo, G., Bernasconi, D., Cola, A., Palmieri, S., Spelzini, F., Milani, R., et al. (2019). Long-term outcomes and five-year recurrence-free survival curves after native-tissue prolapse repair. INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS, 147(2), 238-245 [10.1002/ijgo.12938].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/259524
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