The luminal membrane of larval midgut cells is the site of action of insecticidal delta-endotoxin from Bacillus thuringiensis. At concentrations that correspond to normal effective doses in vivo, the toxin inhibits the uptake of amino acids by brush border membrane vesicles prepared from midguts of Pieris brassicae larvae. The toxin does not interact with the K+-amino acid symport but rather increases the K+ permeability of the membrane. The toxin does not increase the permeability of lepidopteran midgut brush border membrane to either Na+ or H+ nor does it increase the K+ permeability of brush border membrane vesicles prepared from mammalian small intestine,. © 1986.

Sacchi, V., Parenti, P., Hanozet, G., Giordana, B., Luthy, P., & Wolfersberger, M. (1986). Bacillus-thuringiensis toxin inhibits k+-gradient-dependent amino-acid-transport across the brush-border membrane of pieris-brassicae midgut cells. FEBS LETTERS, 204(2), 213-218 [10.1016/0014-5793(86)80814-6].

Bacillus-thuringiensis toxin inhibits k+-gradient-dependent amino-acid-transport across the brush-border membrane of pieris-brassicae midgut cells

PARENTI, PAOLO;
1986-08-18

Abstract

The luminal membrane of larval midgut cells is the site of action of insecticidal delta-endotoxin from Bacillus thuringiensis. At concentrations that correspond to normal effective doses in vivo, the toxin inhibits the uptake of amino acids by brush border membrane vesicles prepared from midguts of Pieris brassicae larvae. The toxin does not interact with the K+-amino acid symport but rather increases the K+ permeability of the membrane. The toxin does not increase the permeability of lepidopteran midgut brush border membrane to either Na+ or H+ nor does it increase the K+ permeability of brush border membrane vesicles prepared from mammalian small intestine,. © 1986.
Articolo in rivista - Articolo scientifico
Scientifica
delta-endotoxin; K+/amino acid cotransport; lepidopteran larvae; BBMV; Bacillus thuringiensis
English
Sacchi, V., Parenti, P., Hanozet, G., Giordana, B., Luthy, P., & Wolfersberger, M. (1986). Bacillus-thuringiensis toxin inhibits k+-gradient-dependent amino-acid-transport across the brush-border membrane of pieris-brassicae midgut cells. FEBS LETTERS, 204(2), 213-218 [10.1016/0014-5793(86)80814-6].
Sacchi, V; Parenti, P; Hanozet, G; Giordana, B; Luthy, P; Wolfersberger, M
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10281/25636
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