Objectives. To implement a new cost efficacy internal Service for blood component irradiation, we carried out specific procedures and quality assurance reports using the linear accelerators (LINACs) of the Regina Elena Institute (IRE) Radiotherapy Department instead of a dedicated device. Methods. The technical aspects, quality assurance and regulatory requirements of the internal procedure to set up a local irradiated blood bank have been defined. The LINACs of the IRE Radiotherapy Department were used to deliver a mean dose of 32 Gy and dose accuracy was checked with gafchromic film. The overall time/cost of this procedure was compared with the previous procedure, out-sourcing the irradiation of blood components. Results: A total of 1996 blood component units were internally irradiated in the first year. Moreover, reducing the overall procedure time by a third. Overall cost/bag of external and internal procedures was approx. 66 and 11 , respectively. Thus the average saving of cost/bag was higher than 80%. The use of gafchromic films in all irradiated blood component bags allowed the accuracy of the dose delivered to blood to be checked. Conclusions: By utilizing LINACs installed in the Radiotherapy Department it is possible to provide an internal blood component irradiation service, capitalizing on internal resources without any inconvenience/discomfort to patients undergoing radiotherapy and satisfying governmental regulatory requirements. The internal irradiation procedures has proven to be safe and feasible, and along with the significant cost/time reduction suggests that it is more advantageous than external procedures. © 2011 Pinnar et al; licensee BioMed Central Ltd

Pinnaro, P., Soriani, A., D'Alessio, D., Giordano, C., Foddai, M., Pinzi, V., et al. (2011). Implementation of a new cost efficacy method for blood irradiation using a non dedicated device. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 30(1) [10.1186/1756-9966-30-7].

Implementation of a new cost efficacy method for blood irradiation using a non dedicated device

Pinzi V.
Penultimo
;
2011

Abstract

Objectives. To implement a new cost efficacy internal Service for blood component irradiation, we carried out specific procedures and quality assurance reports using the linear accelerators (LINACs) of the Regina Elena Institute (IRE) Radiotherapy Department instead of a dedicated device. Methods. The technical aspects, quality assurance and regulatory requirements of the internal procedure to set up a local irradiated blood bank have been defined. The LINACs of the IRE Radiotherapy Department were used to deliver a mean dose of 32 Gy and dose accuracy was checked with gafchromic film. The overall time/cost of this procedure was compared with the previous procedure, out-sourcing the irradiation of blood components. Results: A total of 1996 blood component units were internally irradiated in the first year. Moreover, reducing the overall procedure time by a third. Overall cost/bag of external and internal procedures was approx. 66 and 11 , respectively. Thus the average saving of cost/bag was higher than 80%. The use of gafchromic films in all irradiated blood component bags allowed the accuracy of the dose delivered to blood to be checked. Conclusions: By utilizing LINACs installed in the Radiotherapy Department it is possible to provide an internal blood component irradiation service, capitalizing on internal resources without any inconvenience/discomfort to patients undergoing radiotherapy and satisfying governmental regulatory requirements. The internal irradiation procedures has proven to be safe and feasible, and along with the significant cost/time reduction suggests that it is more advantageous than external procedures. © 2011 Pinnar et al; licensee BioMed Central Ltd
Articolo in rivista - Articolo scientifico
Blood Component Transfusion; Blood Platelets; Calibration; Cost-Benefit Analysis; Graft vs Host Disease; Humans; Lymphocytes; Particle Accelerators; Quality Assurance, Health Care; Time Factors
English
2011
30
1
7
open
Pinnaro, P., Soriani, A., D'Alessio, D., Giordano, C., Foddai, M., Pinzi, V., et al. (2011). Implementation of a new cost efficacy method for blood irradiation using a non dedicated device. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 30(1) [10.1186/1756-9966-30-7].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/255118
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