In the present study, we aimed to confirm the previous finding of an association between GRIK4 and GNB3 variants (rs195478 and rs5443) and remission and treatment resistance in major depression, using a multicenter sample of 223 patients. We did not find any supporting evidence for such associations. These conflicting data may result from difficulties in the replication of candidate gene association studies. Copyright (C) 2012 S. Karger AG, Basel

Serretti, A., Chiesa, A., Crisafulli, C., Massat, I., Linotte, S., Calati, R., et al. (2012). Failure to Replicate Influence of GRIK4 and GNB3 Polymorphisms on Treatment Outcome in Major Depression. NEUROPSYCHOBIOLOGY, 65(2), 70-75 [10.1159/000329553].

Failure to Replicate Influence of GRIK4 and GNB3 Polymorphisms on Treatment Outcome in Major Depression

Calati R;
2012

Abstract

In the present study, we aimed to confirm the previous finding of an association between GRIK4 and GNB3 variants (rs195478 and rs5443) and remission and treatment resistance in major depression, using a multicenter sample of 223 patients. We did not find any supporting evidence for such associations. These conflicting data may result from difficulties in the replication of candidate gene association studies. Copyright (C) 2012 S. Karger AG, Basel
Articolo in rivista - Articolo scientifico
Major depressive disorder, GRIK4, GNB3
English
2012
65
2
70
75
none
Serretti, A., Chiesa, A., Crisafulli, C., Massat, I., Linotte, S., Calati, R., et al. (2012). Failure to Replicate Influence of GRIK4 and GNB3 Polymorphisms on Treatment Outcome in Major Depression. NEUROPSYCHOBIOLOGY, 65(2), 70-75 [10.1159/000329553].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/249240
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