Successful drug delivery to the brain is crucial for the therapy of many neurological disorders, including Alzheimer's disease. A stable tritiated pyrazole curcumin derivative, exhibiting ability to interact with Aβ peptide, has been synthesized to allow tracking studies in an in vitro model of blood brain barrier
Zona, C., LA FERLA, B. (2011). Synthesis of labeled curcumin derivatives as tools for in vitro blood brain barrier trafficking studies. JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 54(9), 629-632 [10.1002/jlcr.1907].
Synthesis of labeled curcumin derivatives as tools for in vitro blood brain barrier trafficking studies
ZONA, CRISTIANO;LA FERLA, BARBARA
2011
Abstract
Successful drug delivery to the brain is crucial for the therapy of many neurological disorders, including Alzheimer's disease. A stable tritiated pyrazole curcumin derivative, exhibiting ability to interact with Aβ peptide, has been synthesized to allow tracking studies in an in vitro model of blood brain barrier
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