The possibility to afford by a biomimetic reaction 'unnatural' products, which could offer a better bioactivity profile than natural analogues, is outlined and the first applications to the synthesis of lignans and related compounds have been reported. Here we describe the synthesis of new heterodimers, having a phenylcoumaran skeleton, by horseradish peroxidase catalyzed cross-coupling reactions of methyl esters of substituted hydroxycinnamic acids

Saliu, F., Tolppa, E., Zoia, L., Orlandi, M. (2011). Horseradish peroxidase catalyzed oxidative cross-coupling reactions: the synthesis of ‘unnatural’ dihydrobenzofuran lignans. TETRAHEDRON LETTERS, 52(30), 3856-3860 [10.1016/j.tetlet.2011.05.072].

Horseradish peroxidase catalyzed oxidative cross-coupling reactions: the synthesis of ‘unnatural’ dihydrobenzofuran lignans

SALIU, FRANCESCO;TOLPPA, EEVA-LIISA;ZOIA, LUCA;ORLANDI, MARCO EMILIO
2011

Abstract

The possibility to afford by a biomimetic reaction 'unnatural' products, which could offer a better bioactivity profile than natural analogues, is outlined and the first applications to the synthesis of lignans and related compounds have been reported. Here we describe the synthesis of new heterodimers, having a phenylcoumaran skeleton, by horseradish peroxidase catalyzed cross-coupling reactions of methyl esters of substituted hydroxycinnamic acids
Articolo in rivista - Articolo scientifico
organic synthesis, radicals, HRP
English
2011
52
30
3856
3860
none
Saliu, F., Tolppa, E., Zoia, L., Orlandi, M. (2011). Horseradish peroxidase catalyzed oxidative cross-coupling reactions: the synthesis of ‘unnatural’ dihydrobenzofuran lignans. TETRAHEDRON LETTERS, 52(30), 3856-3860 [10.1016/j.tetlet.2011.05.072].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/23383
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