Thoracic surgery that requires resection of a portion of lung or of a whole lung profoundly alters the mechanical and fluid dynamic setting of the lung-chest wall coupling, as well as the water balance in the pleural space and in the remaining lung. The most frequent postoperative complications are of a respiratory nature, and their incidence increases the more the preoperative respiratory condition seems compromised. There is an obvious need to identify risk factors concerning mainly the respiratory function, without neglecting the importance of other comorbidities, such as coronary disease. At present, however, a satisfactory predictor of postoperative cardiopulmonary complications is lacking; postoperative morbidity and mortality have remained unchanged in the last 10 years. The aim of this review is to provide a pathophysiologic interpretation of the main respiratory complications of a respiratory nature by relying on new concepts relating to lung fluid dynamics and mechanics. New parameters are proposed to improve evaluation of respiratory function from pre- to the early postoperative period when most of the complications occur.

Miserocchi, G., Beretta, E., Rivolta, I. (2010). Respiratory Mechanics and Fluid Dynamics After Lung Resection Surgery. THORACIC SURGERY CLINICS, 20(3), 345-357 [10.1016/j.thorsurg.2010.03.001].

Respiratory Mechanics and Fluid Dynamics After Lung Resection Surgery

MISEROCCHI, GIUSEPPE ANDREA
;
BERETTA, EGIDIO PAOLO;RIVOLTA, ILARIA
2010

Abstract

Thoracic surgery that requires resection of a portion of lung or of a whole lung profoundly alters the mechanical and fluid dynamic setting of the lung-chest wall coupling, as well as the water balance in the pleural space and in the remaining lung. The most frequent postoperative complications are of a respiratory nature, and their incidence increases the more the preoperative respiratory condition seems compromised. There is an obvious need to identify risk factors concerning mainly the respiratory function, without neglecting the importance of other comorbidities, such as coronary disease. At present, however, a satisfactory predictor of postoperative cardiopulmonary complications is lacking; postoperative morbidity and mortality have remained unchanged in the last 10 years. The aim of this review is to provide a pathophysiologic interpretation of the main respiratory complications of a respiratory nature by relying on new concepts relating to lung fluid dynamics and mechanics. New parameters are proposed to improve evaluation of respiratory function from pre- to the early postoperative period when most of the complications occur.
Articolo in rivista - Articolo scientifico
Air leak; Hydrothorax; Lung edema; Lung interstitial pressure; Overdistension;
English
2010
20
3
345
357
none
Miserocchi, G., Beretta, E., Rivolta, I. (2010). Respiratory Mechanics and Fluid Dynamics After Lung Resection Surgery. THORACIC SURGERY CLINICS, 20(3), 345-357 [10.1016/j.thorsurg.2010.03.001].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/22573
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