PO-345 Long-Term Survivors of Childhood Acute Lymphoblastic Leukaemia (ALL):Does Parents’Emotional Well-being Affect the Emotional Disposition of Their Survived Children?

Background/Objectives: The rate of long-term survival for the Acute Lymphoblastic Leukaemia (ALL) increased during the years. Thus, in the literature the interest for the psychological long-term effects of the treatment of ALL is progressively increased. Parental distress influences parents’ perception of behavioural and emotional problems of their ALL long-term survivors children. Nevertheless, it is unclear whether the parental emotional distress affects child's emotions and behaviour. The aim of this study is to investigate whether parents’ emotional well-being affects the emotional disposition of their ALL long-term survivors children. Design/Methods: A cohort of 70 Italian long-term ALL childhood survivors and their parents were asked to complete respectively the children and the adult Italian version of the Positive and Negative Schedule (PANAS-C; PANAS). Results: Regression models showed that mothers’ PANAS Positive Affect scale (PA) had a statistically significant effect (F4, 45=2.84; P=0.035) on the PA of their ALL long-term survivorschildren(PA-C).Instead,fathers’PANASscalesdid not have any effect on the PA-C (F4, 33= 1.794; P = 0.154). These two results were controlled for children age, children gender and for, respectively, mothers’ and fathers’ PANAS Negative Affect scale (NA). Finally, parents’ PA and NA did notsignificantlyaffecttheNegative AffectscaleoftheirALL survived children (NA-C). Conclusions:In order to enhance the positive emotional disposition of ALL long-term survivors children, this study suggests setting up a psychological intervention focused on their mothers’ positive emotions.