Background: diabetes mellitus (dM) is a highly prevalent disease with severe long-term consequences, and a known risk factor for peripheral artery disease (Pad). These two diseases combined are responsible for high morbidity and mortality. The aim of this study is to investigate the burden of Pad in patients with dM, the effect of revascularization on outcomes, and geographical variation in the access to Pad courses of treatment. METHODS: From the healthcare claims of the Lombardy residents (16% of the Italian population) we identifed diabetic patients with PAD as the study population, distinguishing between patients who received revascularization procedures (revasc) and those who did not (norevasc). Patients were classifed by sex, age, comorbidities, mortality, amputation received and direct healthcare cost. resulTs: The dM with Pad study population consisted of 18,344 patients (61% male), aged on average 72 (±10.1) years. Most of them (64%) did not receive any revascularization procedures and 12% of the latter had at least one major amputation. The major amputation rate was signifcantly lower for the Revasc group when compared to the NoRevasc group. Geographical heterogeneity in DM and PAD occurrences as well as in revascularization procedures was detected in the area under study. ConClusions: The present study gives an up-to-date description of the dramatic epidemiologic and economic burden of Pad in diabetic subjects using a truly population-based data and longitudinal follow-up of up to 9 years. it represented a useful tool to evaluate the impact of revascularization and to provide evidence of different outcomes associated with different levels of access to services

Marone, E., Cozzolino, P., Ciampichini, R., Chiodini, V., Ferraresi, R., Rinaldi, L., et al. (2018). Peripheral arterial disease in diabetic patients: A long-term population-based study on occurrence, outcomes and cost. JOURNAL OF CARDIOVASCULAR SURGERY, 59(4), 572-579 [10.23736/s0021-9509.18.10405-8].

Peripheral arterial disease in diabetic patients: A long-term population-based study on occurrence, outcomes and cost

Ciampichini, Roberta;Mantovani, Lorenzo G.;Cesana, Giancarlo
2018

Abstract

Background: diabetes mellitus (dM) is a highly prevalent disease with severe long-term consequences, and a known risk factor for peripheral artery disease (Pad). These two diseases combined are responsible for high morbidity and mortality. The aim of this study is to investigate the burden of Pad in patients with dM, the effect of revascularization on outcomes, and geographical variation in the access to Pad courses of treatment. METHODS: From the healthcare claims of the Lombardy residents (16% of the Italian population) we identifed diabetic patients with PAD as the study population, distinguishing between patients who received revascularization procedures (revasc) and those who did not (norevasc). Patients were classifed by sex, age, comorbidities, mortality, amputation received and direct healthcare cost. resulTs: The dM with Pad study population consisted of 18,344 patients (61% male), aged on average 72 (±10.1) years. Most of them (64%) did not receive any revascularization procedures and 12% of the latter had at least one major amputation. The major amputation rate was signifcantly lower for the Revasc group when compared to the NoRevasc group. Geographical heterogeneity in DM and PAD occurrences as well as in revascularization procedures was detected in the area under study. ConClusions: The present study gives an up-to-date description of the dramatic epidemiologic and economic burden of Pad in diabetic subjects using a truly population-based data and longitudinal follow-up of up to 9 years. it represented a useful tool to evaluate the impact of revascularization and to provide evidence of different outcomes associated with different levels of access to services
Articolo in rivista - Articolo scientifico
Cost of illness; Diabetes mellitus; Peripheral arterial disease; Adult; Aged; Comorbidity; Costs and Cost Analysis; Diabetes Mellitus; Female; Follow-Up Studies; Humans; Incidence; Italy; Male; Middle Aged; Peripheral Arterial Disease; Prognosis; Retrospective Studies; Survival Rate; Time Factors; Cost of Illness; Population Surveillance; Surgery; Cardiology and Cardiovascular Medicine
English
2018
59
4
572
579
none
Marone, E., Cozzolino, P., Ciampichini, R., Chiodini, V., Ferraresi, R., Rinaldi, L., et al. (2018). Peripheral arterial disease in diabetic patients: A long-term population-based study on occurrence, outcomes and cost. JOURNAL OF CARDIOVASCULAR SURGERY, 59(4), 572-579 [10.23736/s0021-9509.18.10405-8].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/219043
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