SV40-virus-transformed human embryonal fibroblasts show an enhanced chemotactic response to the glycoprotein fibronectin. However, they recognize the same chemotactic active region as non-transformed fibroblasts. The result suggests that an enhancement of chemotaxis by fibroblasts which have been transformed with Simian Virus 40 is due not to the utilization of further chemotactic domains in the molecule, but to an increased sensitivity of the cells to the chemoattractant

Albini, A., Allavena, G., Richter, H., Pontz, B., Parodi, S., Santi, L. (1985). SV40 transformed fibroblasts recognize the same 140 kD fibronectin chemotactic fragment as non-transformed cells. EXPERIENTIA, 41(12), 1591-1593 [10.1007/BF01964822].

SV40 transformed fibroblasts recognize the same 140 kD fibronectin chemotactic fragment as non-transformed cells

ALBINI A;
1985

Abstract

SV40-virus-transformed human embryonal fibroblasts show an enhanced chemotactic response to the glycoprotein fibronectin. However, they recognize the same chemotactic active region as non-transformed fibroblasts. The result suggests that an enhancement of chemotaxis by fibroblasts which have been transformed with Simian Virus 40 is due not to the utilization of further chemotactic domains in the molecule, but to an increased sensitivity of the cells to the chemoattractant
Articolo in rivista - Articolo scientifico
*Cell Transformation, Viral Cells, Cultured Chemotaxis/*drug effects Embryo Fibroblasts/physiology Fibronectins/*pharmacology Human Peptide Fragments/pharmacology Polyomavirus macacae/*physiology
English
1985
41
12
1591
1593
none
Albini, A., Allavena, G., Richter, H., Pontz, B., Parodi, S., Santi, L. (1985). SV40 transformed fibroblasts recognize the same 140 kD fibronectin chemotactic fragment as non-transformed cells. EXPERIENTIA, 41(12), 1591-1593 [10.1007/BF01964822].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/215331
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