The aim of this study was to investigate the lipid content and composition of rat cerebellar granule cells grown in the presence of ethanol (40, 55, or 80 mM) during in vitro differentiation. Quantitative analyses showed no effects of 40 mM ethanol, whereas a significant increase of total cholesterol was observed at 55 mM. Cells exposed to the highest ethanol dose (80 mM) were characterized by a higher sialidase activity, and by the modification of the ganglioside pattern and phospholipid fatty acid composition. The observed modifications were accompanied by changes of membrane anisotropy fluorescence assessed by the fluorescent probe 1,6-diphenyl-1,3,5-hexatriene
Omodeo-Salé, F., Pitto, M., Masserini, M.E., & Palestini, P. (1995). Effects of chronic ethanol exposure on cultured cerebellar granule cells. MOLECULAR AND CHEMICAL NEUROPATHOLOGY, 26(2), 159-169 [10.1007/BF02815010].
Citazione: | Omodeo-Salé, F., Pitto, M., Masserini, M.E., & Palestini, P. (1995). Effects of chronic ethanol exposure on cultured cerebellar granule cells. MOLECULAR AND CHEMICAL NEUROPATHOLOGY, 26(2), 159-169 [10.1007/BF02815010]. | |
Tipo: | Articolo in rivista - Articolo scientifico | |
Carattere della pubblicazione: | Scientifica | |
Presenza di un coautore afferente ad Istituzioni straniere: | No | |
Titolo: | Effects of chronic ethanol exposure on cultured cerebellar granule cells | |
Autori: | Omodeo-Salé, F; Pitto, M; Masserini, ME; Palestini, PNA | |
Autori: | ||
Data di pubblicazione: | 1995 | |
Lingua: | English | |
Rivista: | MOLECULAR AND CHEMICAL NEUROPATHOLOGY | |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1007/BF02815010 | |
Appare nelle tipologie: | 01 - Articolo su rivista |