This study aimed to describe real-life microbiological testing of adults hospitalised with community-acquired pneumonia (CAP) and to assess concordance with the 2007 Infectious Diseases Society of America (IDSA)/American Thoracic Society (ATS) and 2011 European Respiratory Society (ERS) CAP guidelines. This was a cohort study based on the Global Initiative for Methicillin-resistant Staphylococcus aureus Pneumonia (GLIMP) database, which contains point-prevalence data on adults hospitalised with CAP across 54 countries during 2015. In total, 3702 patients were included. Testing was performed in 3217 patients, and included blood culture (71.1%), sputum culture (61.8%), Legionella urinary antigen test (30.1%), pneumococcal urinary antigen test (30.0%), viral testing (14.9%), acute-phase serology (8.8%), bronchoalveolar lavage culture (8.4%) and pleural fluid culture (3.2%). A pathogen was detected in 1173 (36.5%) patients. Testing attitudes varied significantly according to geography and disease severity. Testing was concordant with IDSA/ATS and ERS guidelines in 16.7% and 23.9% of patients, respectively. IDSA/ATS concordance was higher in Europe than in North America (21.5% versus 9.8%; p<0.01), while ERS concordance was higher in North America than in Europe (33.5% versus 19.5%; p<0.01). Testing practices of adults hospitalised with CAP varied significantly by geography and disease severity. There was a wide discordance between real-life testing practices and IDSA/ATS/ERS guideline recommendations.
Carugati, M., Aliberti, S., Reyes, L., Franco Sadud, R., Irfan, M., Prat, C., et al. (2018). Microbiological testing of adults hospitalised with community-acquired pneumonia: an international study. ERJ OPEN RESEARCH, 4(4), 00096-2018.
|Citazione:||Carugati, M., Aliberti, S., Reyes, L., Franco Sadud, R., Irfan, M., Prat, C., et al. (2018). Microbiological testing of adults hospitalised with community-acquired pneumonia: an international study. ERJ OPEN RESEARCH, 4(4), 00096-2018.|
|Tipo:||Articolo in rivista - Articolo scientifico|
|Carattere della pubblicazione:||Scientifica|
|Presenza di un coautore afferente ad Istituzioni straniere:||Si|
|Titolo:||Microbiological testing of adults hospitalised with community-acquired pneumonia: an international study|
|Autori:||Carugati, M; Aliberti, S; Reyes, L; Franco Sadud, R; Irfan, M; Prat, C; Soni, N; Faverio, P; Gori, A; Blasi, F; Restrepo, M|
ALIBERTI, STEFANO (Corresponding)
|Data di pubblicazione:||2018|
|Rivista:||ERJ OPEN RESEARCH|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1183/23120541.00096-2018|
|Appare nelle tipologie:||01 - Articolo su rivista|