Angioedema due to acquired deficiency of the C1-inhibitor is a bridging condition between autoimmunity and lymphoproliferation. We report 32 patients with acquired C1 inhibitor deficiency: 23 have anti C1-inhibitor autoantibodies; 13 have monoclonal gammopathies of unknown significance and 9 have non-Hodgkin's lymphoma. Our series suggest that different forms of B cell disorders coexist and/or evolve into each other in acquired angioedema.

Castelli, R., Deliliers, D., Zingale, L., Pogliani, E., Cicardi, M. (2007). Lymphoproliferative disease and acquired C1 inhibitor deficiency. HAEMATOLOGICA, 92(5), 716-718 [10.3324/haematol.10769].

Lymphoproliferative disease and acquired C1 inhibitor deficiency

POGLIANI, ENRICO MARIA;
2007

Abstract

Angioedema due to acquired deficiency of the C1-inhibitor is a bridging condition between autoimmunity and lymphoproliferation. We report 32 patients with acquired C1 inhibitor deficiency: 23 have anti C1-inhibitor autoantibodies; 13 have monoclonal gammopathies of unknown significance and 9 have non-Hodgkin's lymphoma. Our series suggest that different forms of B cell disorders coexist and/or evolve into each other in acquired angioedema.
Articolo in rivista - Articolo scientifico
Follow-Up Studies; Complement C1 Inhibitor Protein; Angioedema; Disease Progression; Autoantibodies; Paraproteinemias; Lymphoma, Non-Hodgkin; Autoimmune Diseases; Lymphoproliferative Disorders; B-Lymphocytes; Humans; Clone Cells
English
mag-2007
92
5
716
718
none
Castelli, R., Deliliers, D., Zingale, L., Pogliani, E., Cicardi, M. (2007). Lymphoproliferative disease and acquired C1 inhibitor deficiency. HAEMATOLOGICA, 92(5), 716-718 [10.3324/haematol.10769].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/21332
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