Imatinib is an effective treatment for chronic myeloid leukemia (CML) and Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL). However, relapse is common in patients with advanced or high risk disease. Such patients may be eligible for allogeneic stem cell transplantation (SCT), raising the question whether imatinib therapy may compromise the outcome of subsequent SCT.

Deininger, M., Schleuning, M., Greinix, H., Sayer, H., Fischer, T., Martinez, J., et al. (2006). The effect of prior exposure to imatinib on transplant-related mortality. HAEMATOLOGICA, 91(4), 452-459.

The effect of prior exposure to imatinib on transplant-related mortality

POGLIANI, ENRICO MARIA;
2006

Abstract

Imatinib is an effective treatment for chronic myeloid leukemia (CML) and Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL). However, relapse is common in patients with advanced or high risk disease. Such patients may be eligible for allogeneic stem cell transplantation (SCT), raising the question whether imatinib therapy may compromise the outcome of subsequent SCT.
Articolo in rivista - Articolo scientifico
Treatment Outcome; Adolescent; Male; Retrospective Studies; Mortality; Middle Aged; Hematopoietic Stem Cell Transplantation; Female; Child, Preschool; Pyrimidines; Piperazines; Humans; Leukemia; Child; Adult
English
2006
91
4
452
459
none
Deininger, M., Schleuning, M., Greinix, H., Sayer, H., Fischer, T., Martinez, J., et al. (2006). The effect of prior exposure to imatinib on transplant-related mortality. HAEMATOLOGICA, 91(4), 452-459.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/21156
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