Objectives: To evaluate dose reduction and image quality of 80-kV CT pulmonary angiography (CTPA) reconstructed with knowledge model–based iterative reconstruction (IMR), and compared with 100-kV CTPA with hybrid iterative reconstruction (iDose 4 ). Materials and methods: One hundred and fifty-one patients were prospectively investigated for pulmonary embolism; a study group of 76 patients underwent low-kV setting (80 kV, automated mAs) CTPA study, while a control group of 75 patients underwent standard CTPA protocol (100 kV; automated mAs); all patients were examined on 256 MDCT scanner (Philips iCTelite). Study group images were reconstructed using IMR while the control group ones with iDose 4 . CTDIvol, DLP, and ED were evaluated. Region of interests placed in the main pulmonary vessels evaluated vascular enhancement (HU); signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were calculated. Results: Compared to iDose 4 -CTPA, low-kV IMR-CTPA presented lower CTDIvol (6.41 ± 0.84 vs 9.68 ± 3.5 mGy) and DLP (248.24 ± 3.2 vs 352.4 ± 3.59 mGy × cm), with ED of 3.48 ± 1.2 vs 4.93 ± 1.8 mSv. Moreover, IMR-CTPA showed higher values of attenuation (670.91 ± 9.09 HU vs 292.61 ± 15.5 HU) and a significantly higher SNR (p < 0.0001) and CNR (p < 0.0001).The subjective image quality of low-kV IMR-CTPA was also higher compared with iDose 4 -CTPA (p < 0.0001). Conclusions: Low-dose CTPA (80 kV and automated mAs modulation) reconstructed with IMR represents a feasible protocol for the diagnosis of pulmonary embolism in the emergency setting, achieving high image quality with low noise, and a significant dose reduction within adequate reconstruction times(≤ 120 s).

Ippolito, D., De Vito, A., Franzesi, C., Riva, L., Pecorelli, A., Corso, R., et al. (2019). Evaluation of image quality and radiation dose saving comparing knowledge model–based iterative reconstruction on 80-kV CT pulmonary angiography (CTPA) with hybrid iterative reconstruction on 100-kV CT. EMERGENCY RADIOLOGY, 26(2), 145-153 [10.1007/s10140-018-1653-4].

Evaluation of image quality and radiation dose saving comparing knowledge model–based iterative reconstruction on 80-kV CT pulmonary angiography (CTPA) with hybrid iterative reconstruction on 100-kV CT

Ippolito, Davide
;
DE VITO, ANDREA;Franzesi, Cammillo Talei;Pecorelli, Anna;Crespi, Andrea;Sironi, Sandro
2019

Abstract

Objectives: To evaluate dose reduction and image quality of 80-kV CT pulmonary angiography (CTPA) reconstructed with knowledge model–based iterative reconstruction (IMR), and compared with 100-kV CTPA with hybrid iterative reconstruction (iDose 4 ). Materials and methods: One hundred and fifty-one patients were prospectively investigated for pulmonary embolism; a study group of 76 patients underwent low-kV setting (80 kV, automated mAs) CTPA study, while a control group of 75 patients underwent standard CTPA protocol (100 kV; automated mAs); all patients were examined on 256 MDCT scanner (Philips iCTelite). Study group images were reconstructed using IMR while the control group ones with iDose 4 . CTDIvol, DLP, and ED were evaluated. Region of interests placed in the main pulmonary vessels evaluated vascular enhancement (HU); signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were calculated. Results: Compared to iDose 4 -CTPA, low-kV IMR-CTPA presented lower CTDIvol (6.41 ± 0.84 vs 9.68 ± 3.5 mGy) and DLP (248.24 ± 3.2 vs 352.4 ± 3.59 mGy × cm), with ED of 3.48 ± 1.2 vs 4.93 ± 1.8 mSv. Moreover, IMR-CTPA showed higher values of attenuation (670.91 ± 9.09 HU vs 292.61 ± 15.5 HU) and a significantly higher SNR (p < 0.0001) and CNR (p < 0.0001).The subjective image quality of low-kV IMR-CTPA was also higher compared with iDose 4 -CTPA (p < 0.0001). Conclusions: Low-dose CTPA (80 kV and automated mAs modulation) reconstructed with IMR represents a feasible protocol for the diagnosis of pulmonary embolism in the emergency setting, achieving high image quality with low noise, and a significant dose reduction within adequate reconstruction times(≤ 120 s).
Articolo in rivista - Articolo scientifico
Scientifica
Pulmonary embolism; Radiation; Tomography;
Pulmonary embolism; Radiation; Tomography; Emergency Medicine; Radiology, Nuclear Medicine and Imaging
English
Ippolito, D., De Vito, A., Franzesi, C., Riva, L., Pecorelli, A., Corso, R., et al. (2019). Evaluation of image quality and radiation dose saving comparing knowledge model–based iterative reconstruction on 80-kV CT pulmonary angiography (CTPA) with hybrid iterative reconstruction on 100-kV CT. EMERGENCY RADIOLOGY, 26(2), 145-153 [10.1007/s10140-018-1653-4].
Ippolito, D; DE VITO, A; Franzesi, C; Riva, L; Pecorelli, A; Corso, R; Crespi, A; Sironi, S
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10281/211006
Citazioni
  • Scopus 1
  • ???jsp.display-item.citation.isi??? 1
Social impact