Type 1 diabetes is a chronic disease leading to complications such as peripheral neuropathies, nephropathy and cardiovascular disease. Pancreatic islet transplantation is being extensively investigated for blood glucose control in animals and in human type 1 diabetic patients, but the question of whether it can reverse long-term diabetic complications has not been fully explored. We investigated the effects of islet transplantation on diabetic complications in a rat model of streptozotocin-induced diabetes

Remuzzi, A., Cornolti, R., Bianchi, R., Figliuzzi, M., Porretta Serapiglia, C., Oggioni, N., et al. (2009). Regression of diabetic complications by islet transplantation in the rat. DIABETOLOGIA, 52(12), 2653-2661 [10.1007/s00125-009-1537-y].

Regression of diabetic complications by islet transplantation in the rat

OGGIONI, NORBERTO;CAROZZI, VALENTINA ALDA;AVEZZA, FEDERICA;CAVALETTI, GUIDO ANGELO
2009

Abstract

Type 1 diabetes is a chronic disease leading to complications such as peripheral neuropathies, nephropathy and cardiovascular disease. Pancreatic islet transplantation is being extensively investigated for blood glucose control in animals and in human type 1 diabetic patients, but the question of whether it can reverse long-term diabetic complications has not been fully explored. We investigated the effects of islet transplantation on diabetic complications in a rat model of streptozotocin-induced diabetes
Articolo in rivista - Articolo scientifico
Transplantation, Isogeneic; Blood Glucose; Rats, Inbred Lew; Male; Tail; Diabetic Neuropathies; Nociceptors; Rats; Animals; Pain; Humans; Neural Conduction; Diabetes Complications; Thiobarbituric Acid Reactive Substances; Quality of Life; Sodium-Potassium-Exchanging ATPase; Sciatic Nerve; Islets of Langerhans Transplantation; Nerve Fibers
English
2009
52
12
2653
2661
none
Remuzzi, A., Cornolti, R., Bianchi, R., Figliuzzi, M., Porretta Serapiglia, C., Oggioni, N., et al. (2009). Regression of diabetic complications by islet transplantation in the rat. DIABETOLOGIA, 52(12), 2653-2661 [10.1007/s00125-009-1537-y].
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/21028
Citazioni
  • Scopus 33
  • ???jsp.display-item.citation.isi??? 30
Social impact