Silica-encapsulated iron oxide composite nanoparticles were synthesized and characterized in terms of morphological and physico-chemical properties. These nanoparticles exhibited both fluorescent and magnetic properties useful for labeling of breast cancer cells. The mechanism of uptake by tumor cells, the pathway of degradation and the potential toxicity of these magnetofluorescent nanoparticles were investigated, suggesting that they could be developed as an efficient and safe bimodal contrast agent for detection of breast cancer cells. © 2010 American Institute of Physics.

Ronchi, S., Colombo, M., Verderio, P., Mazzucchelli, S., Corsi, F., De Palma, C., et al. (2010). Magnetofluorescent nanoparticles for bimodal detection of breast cancer cells. In Bonsai project symposium: breakthroughs in nanoparticles for bio-imaging (pp.102-105). American Institute of Physics [10.1063/1.3505055].

Magnetofluorescent nanoparticles for bimodal detection of breast cancer cells

COLOMBO, MIRIAM;PROSPERI, DAVIDE
2010

Abstract

Silica-encapsulated iron oxide composite nanoparticles were synthesized and characterized in terms of morphological and physico-chemical properties. These nanoparticles exhibited both fluorescent and magnetic properties useful for labeling of breast cancer cells. The mechanism of uptake by tumor cells, the pathway of degradation and the potential toxicity of these magnetofluorescent nanoparticles were investigated, suggesting that they could be developed as an efficient and safe bimodal contrast agent for detection of breast cancer cells. © 2010 American Institute of Physics.
paper
Nanobiotecnologie; nanoparticelle; tumori; diagnostica
English
BONSAI Project Symposium: Breakthroughs in Nanoparticles for Bio-Imaging - 8/9 april
2010
Bonsai project symposium: breakthroughs in nanoparticles for bio-imaging
978-0-7354-0826-5
2010
1275
102
105
none
Ronchi, S., Colombo, M., Verderio, P., Mazzucchelli, S., Corsi, F., De Palma, C., et al. (2010). Magnetofluorescent nanoparticles for bimodal detection of breast cancer cells. In Bonsai project symposium: breakthroughs in nanoparticles for bio-imaging (pp.102-105). American Institute of Physics [10.1063/1.3505055].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/20669
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