In medical imaging, it remains a challenging and valuable goal how to generate realistic medical images completely different from the original ones; the obtained synthetic images would improve diagnostic reliability, allowing for data augmentation in computer-assisted diagnosis as well as physician training. In this paper, we focus on generating synthetic multi-sequence brain Magnetic Resonance (MR) images using Generative Adversarial Networks (GANs). This involves difficulties mainly due to low contrast MR images, strong consistency in brain anatomy, and intra-sequence variability. Our novel realistic medical image generation approach shows that GANs can generate 128 χ 128 brain MR images avoiding artifacts. In our preliminary validation, even an expert physician was unable to accurately distinguish the synthetic images from the real samples in the Visual Turing Test.

Han, C., Hayashi, H., Rundo, L., Araki, R., Shimoda, W., Muramatsu, S., et al. (2018). GAN-based synthetic brain MR image generation. In Proceedings - International Symposium on Biomedical Imaging (pp.734-738). IEEE Computer Society [10.1109/ISBI.2018.8363678].

GAN-based synthetic brain MR image generation

Rundo, Leonardo;Mauri, Giancarlo;
2018

Abstract

In medical imaging, it remains a challenging and valuable goal how to generate realistic medical images completely different from the original ones; the obtained synthetic images would improve diagnostic reliability, allowing for data augmentation in computer-assisted diagnosis as well as physician training. In this paper, we focus on generating synthetic multi-sequence brain Magnetic Resonance (MR) images using Generative Adversarial Networks (GANs). This involves difficulties mainly due to low contrast MR images, strong consistency in brain anatomy, and intra-sequence variability. Our novel realistic medical image generation approach shows that GANs can generate 128 χ 128 brain MR images avoiding artifacts. In our preliminary validation, even an expert physician was unable to accurately distinguish the synthetic images from the real samples in the Visual Turing Test.
slide + paper
Brain MRI; Data Augmentation; Generative Adversarial Networks; Physician Training; Synthetic Medical Image Generation; Visual Turing Test;
Brain MRI; Data Augmentation; Generative Adversarial Networks; Physician Training; Synthetic Medical Image Generation; Visual Turing Test; Biomedical Engineering; Radiology, Nuclear Medicine and Imaging
English
15th IEEE International Symposium on Biomedical Imaging, ISBI 2018
2018
Proceedings - International Symposium on Biomedical Imaging
9781538636367
2018
2018-
734
738
http://ieeexplore.ieee.org/xpl/conferences.jsp
none
Han, C., Hayashi, H., Rundo, L., Araki, R., Shimoda, W., Muramatsu, S., et al. (2018). GAN-based synthetic brain MR image generation. In Proceedings - International Symposium on Biomedical Imaging (pp.734-738). IEEE Computer Society [10.1109/ISBI.2018.8363678].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/203719
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