The clinical and neurophysiologic data from 65 patients taking thalidomide were reviewed. Thalidomide sensory neurotoxicity was found to be cumulative dose dependent but occurs only when the total dose is relatively high (>20 g). The risk of developing sensory neuropathy is around 10% below this threshold but increases with higher doses.

Cavaletti, G., Beronio, A., Reni, L., Ghiglione, E., Schenone, A., Briani, C., et al. (2004). Thalidomide sensory neurotoxicity: A clinical and neurophysiologic study. NEUROLOGY, 62(12), 2291-2293.

Thalidomide sensory neurotoxicity: A clinical and neurophysiologic study

CAVALETTI, GUIDO ANGELO;FRIGO, MARTA;
2004

Abstract

The clinical and neurophysiologic data from 65 patients taking thalidomide were reviewed. Thalidomide sensory neurotoxicity was found to be cumulative dose dependent but occurs only when the total dose is relatively high (>20 g). The risk of developing sensory neuropathy is around 10% below this threshold but increases with higher doses.
Articolo in rivista - Articolo scientifico
Male; Middle Aged; Female; Thalidomide; Dose-Response Relationship, Drug; Aged; Neurotoxicity Syndromes; Adult; Humans
English
2004
62
12
2291
2293
none
Cavaletti, G., Beronio, A., Reni, L., Ghiglione, E., Schenone, A., Briani, C., et al. (2004). Thalidomide sensory neurotoxicity: A clinical and neurophysiologic study. NEUROLOGY, 62(12), 2291-2293.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/20300
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