The role of Lewis and Bronsted catalysts on the NH3 + HCOOH -> NH2CHO + H2O reaction has been studied ab initio using hydrogen fluoride and trifluoroaluminum as model systems of Bronsted and Lewis catalysts, respectively. Both catalysts, either alone or in combination, have been adopted to activate the synthesis of formamide, the simplest model of a peptide bond containing molecule, by reacting formic acid and ammonia. It has been found that the synergy between both catalysts dramatically lowers the activation barrier for the amide bond formation, a fact relevant in the prebiotic synthesis of peptides on the surface of oxidic minerals rich in Lewis/Bronsted sites. (c) 2005 Elsevier B.V. All rights reserved

Rimola, A., Tosoni, S., Sodupe, M., Ugliengo, P. (2005). Peptide bond formation activated by the interplay of Lewis and Bronsted catalysts. CHEMICAL PHYSICS LETTERS, 408(4-6), 295-301 [10.1016/j.cplett.2005.04.056].

Peptide bond formation activated by the interplay of Lewis and Bronsted catalysts

Tosoni, S;
2005

Abstract

The role of Lewis and Bronsted catalysts on the NH3 + HCOOH -> NH2CHO + H2O reaction has been studied ab initio using hydrogen fluoride and trifluoroaluminum as model systems of Bronsted and Lewis catalysts, respectively. Both catalysts, either alone or in combination, have been adopted to activate the synthesis of formamide, the simplest model of a peptide bond containing molecule, by reacting formic acid and ammonia. It has been found that the synergy between both catalysts dramatically lowers the activation barrier for the amide bond formation, a fact relevant in the prebiotic synthesis of peptides on the surface of oxidic minerals rich in Lewis/Bronsted sites. (c) 2005 Elsevier B.V. All rights reserved
Articolo in rivista - Articolo scientifico
THERMAL CONDENSATION; ALUMINA; GLYCINE; SILICA; MECHANISMS; EFFICIENCY
English
2005
408
4-6
295
301
none
Rimola, A., Tosoni, S., Sodupe, M., Ugliengo, P. (2005). Peptide bond formation activated by the interplay of Lewis and Bronsted catalysts. CHEMICAL PHYSICS LETTERS, 408(4-6), 295-301 [10.1016/j.cplett.2005.04.056].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/197694
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