Introduction: Although improved during the past few years, blood pressure control remains sub optimal. Aim: The impact of follow-up assessment on blood pressure control was evaluated in a group of patients of the HYT (HYperTension survey), treated with a combination of different dihydropyridine calcium-channel blockers (CCBs regimen) and inhibitors of renin-angiotensin-aldosterone system (RAAS) and with uncontrolled blood pressure. This was obtained assessing (a) the rate of blood pressure control at 3 and 6 months of follow-up in the whole group of patients, (b) the rate of blood pressure control and the average blood pressure values in subjects treated with different DHP-CCBs regimen. Methods: From the 4993 patients with uncontrolled blood pressure, (BP ≥ 140/90 or ≥140/85 in patients with diabetes), 3729 (mean age 61.2 ± 11.5 years), maintained CCBs regimen combined wih RAAS blockers and were evaluated at 3 and 6 months follow-up. At each visit BP (semiautomatic device, Omron-M6, 3 measurements), heart rate, adverse events and treatment persistence were collected. Results: At 1st and 2nd follow-up the rate of controlled BP was 63.5 and 72.8% respectively (p < 0.05 vs 35.3% at baseline), whereas in diabetes was 32.5 and 37.9% respectively (p < 0.05 vs 20% at baseline). No differences in heart rate were observed. No differences in control rate were observed between the different CCBs regimen. The incidence of drugs related adverse events was 3.6%. Conclusions: These findings provide evidence that: (a) the follow-up of hypertensive patients under therapy increase the rate of blood pressure control; (b) there is no significant difference in the antihypertensive effect between different CCBs regimen; (c) lipophilic CCBs induce less ankle edema.
Fici, F., Seravalle, G., Koylan, N., Nalbantgil, I., Cagla, N., Korkut, Y., et al. (2017). Follow-up of Antihypertensive Therapy Improves Blood Pressure Control: Results of HYT (HYperTension survey) Follow-up. HIGH BLOOD PRESSURE & CARDIOVASCULAR PREVENTION, 24(3), 289-296 [10.1007/s40292-017-0208-1].
|Citazione:||Fici, F., Seravalle, G., Koylan, N., Nalbantgil, I., Cagla, N., Korkut, Y., et al. (2017). Follow-up of Antihypertensive Therapy Improves Blood Pressure Control: Results of HYT (HYperTension survey) Follow-up. HIGH BLOOD PRESSURE & CARDIOVASCULAR PREVENTION, 24(3), 289-296 [10.1007/s40292-017-0208-1].|
|Tipo:||Articolo in rivista - Articolo scientifico|
|Carattere della pubblicazione:||Scientifica|
|Presenza di un coautore afferente ad Istituzioni straniere:||Si|
|Titolo:||Follow-up of Antihypertensive Therapy Improves Blood Pressure Control: Results of HYT (HYperTension survey) Follow-up|
|Autori:||Fici, F; Seravalle, G; Koylan, N; Nalbantgil, I; Cagla, N; Korkut, Y; Quarti-Trevano, F; Makel, W; Grassi, G|
SERAVALLE, GINO LUCIANO (Secondo)
GRASSI, GUIDO (Ultimo) (Corresponding)
|Data di pubblicazione:||2017|
|Rivista:||HIGH BLOOD PRESSURE & CARDIOVASCULAR PREVENTION|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1007/s40292-017-0208-1|
|Appare nelle tipologie:||01 - Articolo su rivista|