Vicryl® (polyglactin 910) is an absorbable, synthetic, usually braided suture, indicated for soft tissue approximation and ligation. Vicryl® has a special coating for minimizing friction, easing passage through tissue and easy knot tie down. It is synthetic for minimal tissue reaction. Fibroblasts are the main cells of connective tissue that synthesize extracellular matrix. In this work, we tried to judge the action of Vicryl® on fibroblasts behaviour. We evaluated the expression levels of some adhesion and traction-resistance related genes (ELN, DSP, FN1, FBN1, ITGB1, ITGA1, ITGA5, ITGA2, COL1A1, COL3A1) by using real time Reverse Transcription-Polymerase Chain Reaction (real time RT-PCR). All but 2 genes resulted up-regulated after 48 h of treatment. Our preliminary results point out the potential of Vicryl® as a biocompatible and regenerative tool in medicine.
Baj, A., Beltramini, G., Romano, M., Lauritano, D., Gaudio, R., Palmieri, A., et al. (2017). Genetic effects of Vicryl® on fibroblast primary culture. JOURNAL OF BIOLOGICAL REGULATORS & HOMEOSTATIC AGENTS, 31(2), 215-220.
Citazione: | Baj, A., Beltramini, G., Romano, M., Lauritano, D., Gaudio, R., Palmieri, A., et al. (2017). Genetic effects of Vicryl® on fibroblast primary culture. JOURNAL OF BIOLOGICAL REGULATORS & HOMEOSTATIC AGENTS, 31(2), 215-220. | |
Tipo: | Articolo in rivista - Articolo scientifico | |
Carattere della pubblicazione: | Scientifica | |
Presenza di un coautore afferente ad Istituzioni straniere: | No | |
Titolo: | Genetic effects of Vicryl® on fibroblast primary culture | |
Autori: | Baj, A; Beltramini, G; Romano, M; Lauritano, D; Gaudio, R; Palmieri, A; Cura, F; Giannì, A | |
Autori: | ||
Data di pubblicazione: | 2017 | |
Lingua: | English | |
Rivista: | JOURNAL OF BIOLOGICAL REGULATORS & HOMEOSTATIC AGENTS | |
Appare nelle tipologie: | 01 - Articolo su rivista |
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