Ramification of blood circulation is relevant in a number of physiological and pathological conditions. The oxygen exchange occurs largely in the capillary bed, and the cancer progression is closely linked to the angiogenesis around the tumor mass. Optical microscopy has made impressive improvements in in vivo imaging and dynamic studies based on correlation analysis of time stacks of images. Here, we develop and test advanced methods that allow mapping the flow fields in branched vessel networks at the resolution of 10 to 20 μm. The methods, based on the application of spatiotemporal image correlation spectroscopy and its extension to cross-correlation analysis, are applied here to the case of early stage embryos of zebrafish
Ceffa, N., Cesana, I., Collini, M., D'Alfonso, L., Carra, S., Cotelli, F., et al. (2017). Spatiotemporal image correlation analysis of blood flow in branched vessel networks of zebrafish embryos. JOURNAL OF BIOMEDICAL OPTICS, 22(10), 1-7 [10.1117/1.JBO.22.10.106008].
Citazione: | Ceffa, N., Cesana, I., Collini, M., D'Alfonso, L., Carra, S., Cotelli, F., et al. (2017). Spatiotemporal image correlation analysis of blood flow in branched vessel networks of zebrafish embryos. JOURNAL OF BIOMEDICAL OPTICS, 22(10), 1-7 [10.1117/1.JBO.22.10.106008]. | |
Tipo: | Articolo in rivista - Articolo scientifico | |
Carattere della pubblicazione: | Scientifica | |
Presenza di un coautore afferente ad Istituzioni straniere: | No | |
Titolo: | Spatiotemporal image correlation analysis of blood flow in branched vessel networks of zebrafish embryos | |
Autori: | Ceffa, N; Cesana, I; Collini, M; D'Alfonso, L; Carra, S; Cotelli, F; Sironi, L; Chirico, G | |
Autori: | CHIRICO, GIUSEPPE (Corresponding) | |
Data di pubblicazione: | 2017 | |
Lingua: | English | |
Rivista: | JOURNAL OF BIOMEDICAL OPTICS | |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1117/1.JBO.22.10.106008 | |
Appare nelle tipologie: | 01 - Articolo su rivista |
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