The synthesis of protected fucosylated derivatives of a Galβ(1→3)GlcNAc and of lactosamine Galβ(1→4)GlcNAc building blocks contained in human milk oligosaccharides is described. Both chemical and enzymatic methods have been exploited for selective protection of the disaccharide. Fucosylation of the appropriate derivatives allowed an easy and relatively short access to different products from common precursors. © 2002 Elsevier Science Ltd. All rights reserved.

LA FERLA, B., Prosperi, D., Lay, L., Russo, G., & Panza, L. (2002). Synthesis of building blocks of human milk oligosaccharides. Fucosylated derivatives of the lacto- and neolacto series. CARBOHYDRATE RESEARCH, 1333-1342.

Synthesis of building blocks of human milk oligosaccharides. Fucosylated derivatives of the lacto- and neolacto series

LA FERLA, BARBARA;PROSPERI, DAVIDE;
2002

Abstract

The synthesis of protected fucosylated derivatives of a Galβ(1→3)GlcNAc and of lactosamine Galβ(1→4)GlcNAc building blocks contained in human milk oligosaccharides is described. Both chemical and enzymatic methods have been exploited for selective protection of the disaccharide. Fucosylation of the appropriate derivatives allowed an easy and relatively short access to different products from common precursors. © 2002 Elsevier Science Ltd. All rights reserved.
Articolo in rivista - Articolo scientifico
Scientifica
carbohydrate, mimetics
English
LA FERLA, B., Prosperi, D., Lay, L., Russo, G., & Panza, L. (2002). Synthesis of building blocks of human milk oligosaccharides. Fucosylated derivatives of the lacto- and neolacto series. CARBOHYDRATE RESEARCH, 1333-1342.
LA FERLA, B; Prosperi, D; Lay, L; Russo, G; Panza, L
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10281/17056
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