Chronic exposure to ethanol (6% in the drinking water, 25 days) reduces the responsiveness of both the dopamine-stimulated and of the dopamine-inhibited adenylate cyclase in rat striatum. The changes in the adenylate cyclase activity are paralleled by alterations in dopamine recognition sites, in fact binding studies using selective ligands indicate that the number of both D1- and D2-receptors is reduced in striatal membranes of treated rats.

Lucchi, L., Moresco, R., Govoni, S., Trabucchi, M. (1988). Effect of chronic ethanol treatment on dopamine receptor subtypes in rat striatum. BRAIN RESEARCH, 449(1-2), 347-351 [10.1016/0006-8993(88)91051-7].

Effect of chronic ethanol treatment on dopamine receptor subtypes in rat striatum

MORESCO, ROSA MARIA;
1988

Abstract

Chronic exposure to ethanol (6% in the drinking water, 25 days) reduces the responsiveness of both the dopamine-stimulated and of the dopamine-inhibited adenylate cyclase in rat striatum. The changes in the adenylate cyclase activity are paralleled by alterations in dopamine recognition sites, in fact binding studies using selective ligands indicate that the number of both D1- and D2-receptors is reduced in striatal membranes of treated rats.
Articolo in rivista - Articolo scientifico
Ethanol; Dopamine receptor; Striatum; Adenylate cyclase
English
1988
449
1-2
347
351
none
Lucchi, L., Moresco, R., Govoni, S., Trabucchi, M. (1988). Effect of chronic ethanol treatment on dopamine receptor subtypes in rat striatum. BRAIN RESEARCH, 449(1-2), 347-351 [10.1016/0006-8993(88)91051-7].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/17000
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