Positron emission tomography (PET) allows the non invasive and quantitative measurement of regional distribution of molecules labeled with positron emitting isotopes such as: nitrogen, oxygen, carbon and fluorine. The aim of the present paper is to review the applications of this methodology for the in vivo study of the kinetics and of the mechanism of action of drugs in humans.
Lucignani, G., Moresco, R., Fazio, F. (1993). Positron emission tomography in pharmacokinetics and pharmacodynamics. BOLLETTINO CHIMICO FARMACEUTICO, 132, 231-233.
Positron emission tomography in pharmacokinetics and pharmacodynamics
MORESCO, ROSA MARIA;FAZIO, FERRUCCIO
1993
Abstract
Positron emission tomography (PET) allows the non invasive and quantitative measurement of regional distribution of molecules labeled with positron emitting isotopes such as: nitrogen, oxygen, carbon and fluorine. The aim of the present paper is to review the applications of this methodology for the in vivo study of the kinetics and of the mechanism of action of drugs in humans.
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