Stereo- and regioselective acylation and deacylation of carbohydrates can be achieved using lipases as biocatalysts. These enzymes are extremely versatile, quite stable in aqueous and organic solvents, easily available, and easy to handle. Recently, they have become the object of site directed mutagenesis which suggests that they soon could be 'built ad hoc' for specific necessities.
LA FERLA, B. (2002). Lipases as useful tools for the stereo- and regioselective protection and deprotection of carbohydrates. MONATSHEFTE FÜR CHEMIE, 133(4), 351-368 [10.1007/s007060200015].
Lipases as useful tools for the stereo- and regioselective protection and deprotection of carbohydrates
LA FERLA, BARBARA
2002
Abstract
Stereo- and regioselective acylation and deacylation of carbohydrates can be achieved using lipases as biocatalysts. These enzymes are extremely versatile, quite stable in aqueous and organic solvents, easily available, and easy to handle. Recently, they have become the object of site directed mutagenesis which suggests that they soon could be 'built ad hoc' for specific necessities.
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