The synthesis of novel hyperbranched monodisperse linear dendrimers, based on 2,2-bis-(hydroxymethyl)-propionic acid (bis-MPA), has been achieved by convergent metathesis-mediated coupling between the alkene-terminated focal point of bis-MPA dendrons. On their surface, dendrimers present 4, 8 and 16 functional groups. Glycodendrimers exposing multiple saccharide moieties have also been obtained. To the best of our knowledge, this is the first example of the use of metathesis for focal point coupling.
Guizzardi, R., Vacchini, M., Santambrogio, C., & Cipolla, L. (2017). Convergent dendrimer synthesis by olefin metathesis and studies toward glycoconjugation. CANADIAN JOURNAL OF CHEMISTRY, 95(9), 1008-1012.
Citazione: | Guizzardi, R., Vacchini, M., Santambrogio, C., & Cipolla, L. (2017). Convergent dendrimer synthesis by olefin metathesis and studies toward glycoconjugation. CANADIAN JOURNAL OF CHEMISTRY, 95(9), 1008-1012. |
Tipo: | Articolo in rivista - Articolo scientifico |
Carattere della pubblicazione: | Scientifica |
Presenza di un coautore afferente ad Istituzioni straniere: | No |
Titolo: | Convergent dendrimer synthesis by olefin metathesis and studies toward glycoconjugation |
Autori: | Guizzardi, R; Vacchini, M; Santambrogio, C; Cipolla, L |
Autori: | GUIZZARDI, ROBERTO (Primo) VACCHINI, MATTIA (Secondo) SANTAMBROGIO, CARLO (Penultimo) CIPOLLA, LAURA FRANCESCA (Ultimo) (Corresponding) |
Data di pubblicazione: | 2017 |
Lingua: | English |
Rivista: | CANADIAN JOURNAL OF CHEMISTRY |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1139/cjc-2017-0146 |
Appare nelle tipologie: | 01 - Articolo su rivista |