Bicyclic amino acids derived from the natural sugars D-arabinofuranose and D-fructofuranose have been synthesised; their ability to induce a turn conformation in peptides has been exploited in the preparation of a cyclic RGD loop mimetic.
Peri, F., Cipolla, L., LA FERLA, B., Nicotra, F. (2000). Synthesis of bicyclic sugar azido acids and their incorporation in cyclic peptides. CHEMICAL COMMUNICATIONS(23), 2303-2304 [10.1039/b006192l].
Synthesis of bicyclic sugar azido acids and their incorporation in cyclic peptides
PERI, FRANCESCO;CIPOLLA, LAURA FRANCESCA;LA FERLA, BARBARA;NICOTRA, FRANCESCO
2000
Abstract
Bicyclic amino acids derived from the natural sugars D-arabinofuranose and D-fructofuranose have been synthesised; their ability to induce a turn conformation in peptides has been exploited in the preparation of a cyclic RGD loop mimetic.
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