There is general agreement that type 2 diabetes is the consequence of insulin resistance, defined as an impaired ability of insulin to control hepatic and peripheral glucose metabolism, and of compromised pancreatic β-cell function such that insulin secretion is insufficient to compensate the degree of insulin resistance [1]. The pivotal role of insulin resistance is confirmed by the fact that it is a consistent finding in patients with type 2 diabetes. Indeed, insulin resistance may be detected 10-20 years before the onset of overt hyperglycemia and prospective studies have demonstrated that it is the best predictor of whether an individual will later become diabetic [2]
Perseghin, G. (2011). Excessive nutrients and regional energy metabolism. In Cellular Physiology and Metabolism of Physical Exercise (pp. 55-66). Springer-Verlag Italia s.r.l..
Citazione: | Perseghin, G. (2011). Excessive nutrients and regional energy metabolism. In Cellular Physiology and Metabolism of Physical Exercise (pp. 55-66). Springer-Verlag Italia s.r.l.. |
Titolo: | Excessive nutrients and regional energy metabolism |
Autori: | Perseghin, G |
Autori: | PERSEGHIN, GIANLUCA (Primo) |
Presenza di un coautore afferente ad Istituzioni straniere: | No |
Tipo: | Capitolo o saggio |
Carattere della pubblicazione: | Scientifica |
Data di pubblicazione: | 2011 |
Lingua: | English |
Titolo del libro: | Cellular Physiology and Metabolism of Physical Exercise |
ISBN: | 978-884702418-2 |
Appare nelle tipologie: | 03 - Contributo in libro |