Chemotherapy-induced peripheral neurotoxicity (CIPN) is a potentially dose-limiting side effect of the treatment of several cancers. CIPN is predominantly or exclusively sensory, and it is frequently associated with unpleasant symptoms, overall referred to as “pain.” However, given the markedly different clinical presentation and course of CIPN depending on the antineoplastic drug used, the broad term “pain” in the specific context of CIPN needs to be reconsidered and refined. In fact, a precise identification of the features of CIPN has relevant implication in the design of rational-based clinical trials and in the selection of possible active drugs.

Marmiroli, P., Scuteri, A., Cornblath, D., Cavaletti, G. (2017). Pain in chemotherapy-induced peripheral neurotoxicity. JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM, 22(3), 156-161 [10.1111/jns.12226].

Pain in chemotherapy-induced peripheral neurotoxicity

MARMIROLI, PAOLA LORENA
Primo
;
SCUTERI, ARIANNA
Secondo
;
CAVALETTI, GUIDO ANGELO
Ultimo
2017

Abstract

Chemotherapy-induced peripheral neurotoxicity (CIPN) is a potentially dose-limiting side effect of the treatment of several cancers. CIPN is predominantly or exclusively sensory, and it is frequently associated with unpleasant symptoms, overall referred to as “pain.” However, given the markedly different clinical presentation and course of CIPN depending on the antineoplastic drug used, the broad term “pain” in the specific context of CIPN needs to be reconsidered and refined. In fact, a precise identification of the features of CIPN has relevant implication in the design of rational-based clinical trials and in the selection of possible active drugs.
Articolo in rivista - Articolo scientifico
Chemotherapy; Clinical trial; Neurotoxicity; Pain; Neuroscience (all); Neurology (clinical)
English
2017
22
3
156
161
none
Marmiroli, P., Scuteri, A., Cornblath, D., Cavaletti, G. (2017). Pain in chemotherapy-induced peripheral neurotoxicity. JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM, 22(3), 156-161 [10.1111/jns.12226].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/164957
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