The present chapter is focused on the role of positron emission tomography/computed tomography (PET/CT) and [11C]-labelled Choline ([11C]Choline) for the management of prostate cancer patients for radiation therapy planning. Although still a matter of debate, PET/CT with [11C]Choline is not routinely recommended for selecting patients for prostate cancer primary radiation treatment. However, due to its high accuracy in detecting and localizing recurrences when a biochemical failure occurs, [11C]Choline PET/CT may play a role in the re-staging phase to distinguish patients with local versus distant relapse, thus influencing patient management (curative versus palliative therapy). Limited data are currently available on the role of [11C]Choline PET/CT in target volume selection and delineation. According to available literature, [11C]Choline PET/CT is not clinically recommendable to plan target volume both for primary prostate treatment and for local recurrence. Nevertheless, promising data suggested a potential role of [11C]Choline PET/CT as an image guide tool for the irradiation of prostate cancer relapse.

Picchio, M., Giovannini, E., Crivellaro, C., Gianolli, L., Muzio, N., Messa, M. (2010). Clinical evidence on PET/CT for radiation therapy planning in prostate cancer. RADIOTHERAPY AND ONCOLOGY, 96(3), 347-350 [10.1016/j.radonc.2010.07.016].

Clinical evidence on PET/CT for radiation therapy planning in prostate cancer

CRIVELLARO, CINZIA;MESSA, MARIA CRISTINA
2010

Abstract

The present chapter is focused on the role of positron emission tomography/computed tomography (PET/CT) and [11C]-labelled Choline ([11C]Choline) for the management of prostate cancer patients for radiation therapy planning. Although still a matter of debate, PET/CT with [11C]Choline is not routinely recommended for selecting patients for prostate cancer primary radiation treatment. However, due to its high accuracy in detecting and localizing recurrences when a biochemical failure occurs, [11C]Choline PET/CT may play a role in the re-staging phase to distinguish patients with local versus distant relapse, thus influencing patient management (curative versus palliative therapy). Limited data are currently available on the role of [11C]Choline PET/CT in target volume selection and delineation. According to available literature, [11C]Choline PET/CT is not clinically recommendable to plan target volume both for primary prostate treatment and for local recurrence. Nevertheless, promising data suggested a potential role of [11C]Choline PET/CT as an image guide tool for the irradiation of prostate cancer relapse.
Articolo in rivista - Articolo scientifico
Prostate; Choline; PET; Recurrence
English
2010
96
3
347
350
none
Picchio, M., Giovannini, E., Crivellaro, C., Gianolli, L., Muzio, N., Messa, M. (2010). Clinical evidence on PET/CT for radiation therapy planning in prostate cancer. RADIOTHERAPY AND ONCOLOGY, 96(3), 347-350 [10.1016/j.radonc.2010.07.016].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/16262
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