Preeclampsia is a pregnancy-specific multisystem disorder, complicating 2-8% of pregnancies, and represents a leading cause of maternal and perinatal morbidity and mortality. Recent investigations have elucidated the understanding of its underlying pathogenic mechanisms. However, despite these advances, therapeutic approaches are still severely limited. Ongoing lines of research indicate some potential novel therapeutic options, targeting the etiopathogenic pathways and, thus, offering hope for effective pharmacologic interventions to be available in the near future. In this editorial, we will give an updated overview of Preeclampsia pathogenesis and promising emerging therapeutic options. © 2014 Informa UK Ltd

Ornaghi, S., Paidas, M. (2014). Upcoming drugs for the treatment of preeclampsia in pregnant women. EXPERT REVIEW OF CLINICAL PHARMACOLOGY, 7(5), 599-603 [10.1586/17512433.2014.944501].

Upcoming drugs for the treatment of preeclampsia in pregnant women

ORNAGHI, SARA
Primo
;
2014

Abstract

Preeclampsia is a pregnancy-specific multisystem disorder, complicating 2-8% of pregnancies, and represents a leading cause of maternal and perinatal morbidity and mortality. Recent investigations have elucidated the understanding of its underlying pathogenic mechanisms. However, despite these advances, therapeutic approaches are still severely limited. Ongoing lines of research indicate some potential novel therapeutic options, targeting the etiopathogenic pathways and, thus, offering hope for effective pharmacologic interventions to be available in the near future. In this editorial, we will give an updated overview of Preeclampsia pathogenesis and promising emerging therapeutic options. © 2014 Informa UK Ltd
Recensione in rivista
anti-digoxin antibody; endothelial dysfunction; lipid apheresis; mesenchymal stem cells; nitric oxide modulators; Preeclampsia; recombinant human antithrombin; RLX030; statins; Animals; Female; Humans; Pre-Eclampsia; Pregnancy; Drug Design; Maternal Mortality; Pharmacology (medical); Pharmacology, Toxicology and Pharmaceutics (all); Medicine (all)
English
2014
7
5
599
603
none
Ornaghi, S., Paidas, M. (2014). Upcoming drugs for the treatment of preeclampsia in pregnant women. EXPERT REVIEW OF CLINICAL PHARMACOLOGY, 7(5), 599-603 [10.1586/17512433.2014.944501].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/157352
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