Alcohol and tobacco, alone or in combination, are associated with an increased risk of various cancers, including those of the upper aero-digestive tract and liver. Both alcohol and tobacco use can increase the risk of cancer of the oral cavity and throat (pharynx, and their combined use has a multiplicative effect on risk. Moreover, those regions of the mouth and pharynx that are more directly exposed to alcohol or tobacco are more likely to be affected by cancer than other regions. A similar effect was found with respect to cancer of the voice box (larynx). For squamous cell carcinoma of the esophagus, alcohol and tobacco also appear to increase risk synergistically. With liver cancer, in contrast, alcohol consumption and tobaacco use appear to be independent risk factors.

Pelucchi, C., Gallus, S., Garavello, W., Bosetti, C., La Vecchia, C. (2006). Cancer risk associated with alcohol and tobacco use: Focus on upper aero-digestive tract and liver. ALCOHOL RESEARCH & HEALTH, 29(3), 193-198.

Cancer risk associated with alcohol and tobacco use: Focus on upper aero-digestive tract and liver

GARAVELLO, WERNER;
2006

Abstract

Alcohol and tobacco, alone or in combination, are associated with an increased risk of various cancers, including those of the upper aero-digestive tract and liver. Both alcohol and tobacco use can increase the risk of cancer of the oral cavity and throat (pharynx, and their combined use has a multiplicative effect on risk. Moreover, those regions of the mouth and pharynx that are more directly exposed to alcohol or tobacco are more likely to be affected by cancer than other regions. A similar effect was found with respect to cancer of the voice box (larynx). For squamous cell carcinoma of the esophagus, alcohol and tobacco also appear to increase risk synergistically. With liver cancer, in contrast, alcohol consumption and tobaacco use appear to be independent risk factors.
Articolo in rivista - Articolo scientifico
Liver Neoplasms; Cocarcinogenesis; Carcinoma, Hepatocellular; Tobacco Use Disorder; Oropharyngeal Neoplasms; Alcohol-Induced Disorders; Risk Factors; Esophageal Neoplasms; Laryngeal Neoplasms; Carcinoma, Squamous Cell; Humans
English
2006
29
3
193
198
none
Pelucchi, C., Gallus, S., Garavello, W., Bosetti, C., La Vecchia, C. (2006). Cancer risk associated with alcohol and tobacco use: Focus on upper aero-digestive tract and liver. ALCOHOL RESEARCH & HEALTH, 29(3), 193-198.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/15325
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