Phosphaturic mesenchymal tumors that cause the paraneoplastic syndrome known as oncogenic osteomalacia are rare. The authors report on the case of a 57-year-old man with a history of osteomalacia and in whom was diagnosed a thoracic spine tumor at the T-4 level. Complete tumor resection was accomplished. The histological diagnosis was phosphaturic mesenchymal tumor (mixed connective tissue variant). After lesion removal, the paraneoplastic syndrome resolved. At the 24-month follow-up, no recurrence of the disease was observed. The clinical presentation, surgical technique, and follow-up in this case were reviewed in detail.

Pirola, E., Vergani, F., Casiraghi, P., Leone, E., Guerra, P., Sganzerla, E., et al. (2009). Oncogenic osteomalacia caused by a phosphaturic mesenchymal tumor of the thoracic spine. JOURNAL OF NEUROSURGERY. SPINE, 10(4), 329-333 [10.3171/2009.1.SPINE08351].

Oncogenic osteomalacia caused by a phosphaturic mesenchymal tumor of the thoracic spine

PIROLA, ELENA;VERGANI, FRANCESCO;CASIRAGHI, PAOLO;SGANZERLA, ERIK PIETRO;LEONE, BIAGIO EUGENIO
2009

Abstract

Phosphaturic mesenchymal tumors that cause the paraneoplastic syndrome known as oncogenic osteomalacia are rare. The authors report on the case of a 57-year-old man with a history of osteomalacia and in whom was diagnosed a thoracic spine tumor at the T-4 level. Complete tumor resection was accomplished. The histological diagnosis was phosphaturic mesenchymal tumor (mixed connective tissue variant). After lesion removal, the paraneoplastic syndrome resolved. At the 24-month follow-up, no recurrence of the disease was observed. The clinical presentation, surgical technique, and follow-up in this case were reviewed in detail.
Articolo in rivista - Articolo scientifico
Male; Hypophosphatemia, Familial; Thoracic Vertebrae; Mesenchymoma; Middle Aged; Osteomalacia; Magnetic Resonance Imaging; Spinal Fusion; Paraneoplastic Syndromes; Spinal Neoplasms; Humans
English
329
333
Pirola, E., Vergani, F., Casiraghi, P., Leone, E., Guerra, P., Sganzerla, E., et al. (2009). Oncogenic osteomalacia caused by a phosphaturic mesenchymal tumor of the thoracic spine. JOURNAL OF NEUROSURGERY. SPINE, 10(4), 329-333 [10.3171/2009.1.SPINE08351].
Pirola, E; Vergani, F; Casiraghi, P; Leone, E; Guerra, P; Sganzerla, E; Leone, B
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/14447
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